Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CCR8 | P51685 | 2/20 | 0.37 |
| ▸ | PTGES | O14684 | 9/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13612704 | 0.92 | RXFP1 (0.38) | TP53CCR8PTGESRXFP1MEN1 | |
| SCHEMBL13612662 | 0.90 | RXFP1 (0.36) | CCR8PTGESRXFP1ALDH1A1LMNA | |
| SCHEMBL7095561 | 0.87 | KMT2A (0.44) | TP53PTGESRXFP1KMT2AALDH1A1 | |
| SCHEMBL13612669 | 0.85 | CCR8 (0.36) | TP53CCR8PTGESRXFP1ALDH1A1 | |
| SCHEMBL18400025 | 0.85 | TP53 (0.46) | TP53RXFP1ALDH1A1POLBLMNA | |
| SCHEMBL12996758 | 0.84 | ALDH1A1 (0.38) | TP53CCR8RXFP1ALDH1A1LMNA | |
| Flubendiamide SCHEMBL29369179 | 0.83 | EPHX2 (0.36) | TP53CCR8RXFP1ALDH1A1LMNA | |
| Flubendiamide SCHEMBL4054589 | 0.83 | EPHX2 (0.36) | TP53CCR8RXFP1ALDH1A1LMNA | |
| Flubendiamide SCHEMBL27362 | 0.83 | EPHX2 (0.36) | TP53CCR8RXFP1ALDH1A1LMNA | |
| Flubendiamide SCHEMBL15798517 | 0.82 | EPHX2 (0.35) | TP53CCR8RXFP1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612018-B2 | Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-20080214393-A1 | Novel Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214393-A1 | Novel Insecticides | DDT, CYP4F11, ACHE | TP53 4642/4885CCR8 4295/4885PTGES 2794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.