Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098147 | 0.86 | EPHX1 (0.41) | CYP2D6CYP2C19EPHX1 | |
| SCHEMBL7097230 | 0.79 | CYP2D6 (0.41) | CYP2D6CYP2C19ADH1BADH1CADH1A | |
| SCHEMBL7100804 | 0.72 | HPGD (0.40) | CYP2C19HPGD | |
| SCHEMBL3972742 | 0.70 | CYP2D6 (0.38) | CYP2D6CYP2C19MMP1MMP8EPHX1 | |
| SCHEMBL7441359 | 0.64 | HPGD (0.53) | CYP2D6CYP2C19MMP1MMP8EPHX1 | |
| SCHEMBL11798160 | 0.63 | HPGD (0.51) | CYP2D6CYP2C19EPHX1HPGD | |
| SCHEMBL26859064 | 0.63 | CYP2D6 (0.45) | CYP2D6CYP2C19MMP1MMP8EPHX1 | |
| Water SCHEMBL10443430 | 0.63 | HPGD (0.51) | CYP2D6CYP2C19MMP1MMP8EPHX1 | |
| SCHEMBL7094106 | 0.62 | CYP2D6 (0.41) | CYP2D6CYP2C19MMP1MMP8HPGD | |
| SCHEMBL6344936 | 0.62 | HPGD (0.54) | CYP2D6CYP2C19MMP1MMP8EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815084-B1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | EP | claimed |
| EP-0815084-B1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | EP | disclosed |