Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | EPOR | P19235 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 2/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098463 | 0.85 | ALDH1A1 (0.40) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL7097121 | 0.81 | TLR2 (0.42) | HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL7515528 | 0.80 | SLC1A3 (0.38) | ALDH1A1MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL7100866 | 0.77 | HPGD (0.48) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL11028392 | 0.75 | MME (0.40) | HPGDALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL8910551 | 0.74 | PTGES (0.42) | CTSB | |
| SCHEMBL27530431 | 0.74 | CTSB (0.44) | ALDH1A1MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL10694799 | 0.74 | LAP3 (0.44) | HPGDALDH1A1CTSB | |
| SCHEMBL7095567 | 0.72 | CYP2D6 (0.35) | HPGDCYP2C19 | |
| SCHEMBL10540689 | 0.72 | MAPT (0.42) | MAPTFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815084-B1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | EP | disclosed |
| US-5672598-A | MATRIX METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-30 | — | — | US | disclosed |