SCHEMBL709559

SCHEMBL709559

O=C(O)c1c(F)c(F)c(Cc2c(F)c(F)c(C(=O)O)c(C(=O)O)c2F)c(F)c1C(=O)O

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.32
PKM P14618 1/20 0.32
HTT P42858 1/20 0.32
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
CRHBP P24387 1/20 0.32
CRHR2 Q13324 1/20 0.32
TSHR P16473 1/20 0.31
CES2 O00748 1/20 0.30
CES1 P23141 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4674767 0.81 DUSP3 (0.35) SMN1; SMN2PKMHTTMEN1KMT2A
SCHEMBL13927505 0.79
SCHEMBL336394 0.78 CES2 (0.43) SMN1; SMN2PKMHTTMEN1KMT2A
SCHEMBL1635048 0.78 CYP1A2 (0.38) SMN1; SMN2PKMHTTMEN1KMT2A
SCHEMBL29449985 0.78 CES2 (0.43) SMN1; SMN2PKMHTTMEN1KMT2A
SCHEMBL8775371 0.76 ALDH1A1 (0.35) SMN1; SMN2PKMMEN1KMT2ACRHBP
SCHEMBL10454093 0.75 CES2 (0.42) SMN1; SMN2PKMHTTMEN1KMT2A
Ammonia Solution, Strong SCHEMBL10455117 0.75 CES2 (0.42) SMN1; SMN2PKMHTTMEN1KMT2A
Fluoride SCHEMBL10713010 0.75 CES2 (0.42) SMN1; SMN2PKMHTTMEN1KMT2A
SCHEMBL5014711 0.75 CES2 (0.42) SMN1; SMN2PKMHTTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6391932-B1 DIELECTRIC POLYIMIDE SHIPLEY COMPANY, L.L.C. 2002-05-21 US claimed
EP-0698052-B1 NEGATIVE BIREFRINGENT POLYIMIDE FILMS UNIV AKRON (US) 2000-06-14 EP claimed
JP-H08511812-A 1996-12-10 JP claimed
EP-0698052-A4 NEGATIVE BIREFRINGENT POLYIMIDE FILMS UNIV AKRON (US) 1996-08-07 EP claimed
EP-0698052-A1 NEGATIVE BIREFRINGENT POLYIMIDE FILMS The University of Akron (US) 1996-02-28 EP claimed
US-5480964-A CONTROLLING ORIENTATION BY SUBSTITUTION ON AROMATIC BACKBONE THE UNIVERSITY OF AKRON (US) 1996-01-02 US claimed
US-5395918-A Heat resistance, electrical resistance and mechanical properties THE UNIVERSITY OF AKRON (US) 1995-03-07 US claimed
WO-1994024191-A1 NEGATIVE BIREFRINGENT POLYIMIDE FILMS THE UNIVERSITY OF AKRON (US) 1994-10-27 WO claimed
US-5344916-A Multilayer films for optical displays using polyimide films THE UNIVERSITY OF AKRON (US) 1994-09-06 US claimed
US-5328979-A Thermoplastic copolyimides and composites therefrom THE UNIVERSITY OF AKRON (US) 1994-07-12 US claimed
US-9494720-B2 Polarizing film, laminated film, and liquid crystal display NITTO DENKO CORPORATION (JP) 2016-11-15 US disclosed
US-9465253-B2 Liquid crystal display apparatus having excellent viewing angle compensation NITTO DENKO CORPORATION (JP) 2016-10-11 US disclosed
EP-2493991-B1 ANTIREFLECTIVE COMPOSITION FOR PHOTORESISTS MERCK PATENT GMBH (DE) 2016-03-02 EP disclosed
US-20150109564-A1 POLARIZING PLATE WITH AN OPTICAL COMPENSATION LAYER, LIQUID CRYSTAL PANEL, LIQUID CRYSTAL DISPLAY APPARATUS, AND IMAGE DISPLAY APPARATUS USING THE POLARIZING PLATE WITH AN OPTICAL COMPENSATION LAYER NITTO DENKO CORPORATION (JP) 2015-04-23 US disclosed
EP-2191059-B1 COATED FIBER AND METHOD FOR MAKING THE COATED FIBER SABIC INNOVATIVE PLASTICS IP (NL) 2015-04-01 EP disclosed
US-4158731-A PHOTOSENSITIVE POLYAMIDES CONTAINING MALEIMIDE GROUPS CIBA-GEIGY CORPORATION (US) 1979-06-19 US disclosed
US-4124651-A Process for the production of polyamide-polyamide-acid copolymers CIBA-GEIGY CORPORATION (US) 1978-11-07 US disclosed
US-4115359-A Crosslinkable polymers prepared from maleimidyl substituted trimellitic acid compounds CIBA-GEIGY CORPORATION (US) 1978-09-19 US disclosed
US-4115368-A Crosslinkable polymers of compounds containing 5-maleimidyl-isophthalic acid derivatives CIBA-GEIGY CORPORATION (US) 1978-09-19 US disclosed
US-4079041-A CONTAINING PHOTOSENSITIVE MALEIMIDO GROUPS, PHOTOCURABLE CIBA-GEIGY CORPORATION (US) 1978-03-14 US disclosed