Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 1/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 6/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7095730 | 1.00 | NOS2 (0.57) | NOS2GRIN2BGRIN1LMNAALDH1A1 | |
| SCHEMBL22068857 | 0.87 | NOS2 (0.65) | NOS2GRIN2BGRIN1ALDH1A1GRIN2D | |
| SCHEMBL22068858 | 0.87 | NOS2 (0.65) | NOS2GRIN2BGRIN1ALDH1A1GRIN2D | |
| SCHEMBL29410307 | 0.80 | ALDH1A1 (0.52) | GRIN2BGRIN1LMNAALDH1A1SCN2A | |
| SCHEMBL28113284 | 0.79 | NOS2 (0.57) | NOS2GRIN2BGRIN1ALDH1A1SCN2A | |
| SCHEMBL104888 | 0.78 | NOS2 (0.65) | NOS2GRIN2BGRIN1ALDH1A1GRIN2D | |
| SCHEMBL25315588 | 0.78 | NOS2 (0.55) | NOS2GRIN2BGRIN1ALDH1A1GRIN2D | |
| SCHEMBL30532640 | 0.78 | NOS2 (0.55) | NOS2GRIN2BGRIN1ALDH1A1GRIN2D | |
| SCHEMBL29066796 | 0.78 | NOS2 (0.55) | NOS2GRIN2BGRIN1ALDH1A1GRIN2D | |
| SCHEMBL9197041 | 0.76 | NOS2 (0.53) | NOS2GRIN2BGRIN1ALDH1A1SCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003084662-A2 | COVALENTLY FIXED LIGAND SYSTEMS, NON-METALLOCENE SYSTEMS AND CATALYST SYSTEMS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF FOR POLYMERIZING OLEFINS | CELANESE VENTURES GMBH (DE) | 2003-10-16 | — | — | WO | disclosed |