Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | XBP1 | P17861 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL186411 | 0.95 | LMNA (0.32) | LMNAMAPTXBP1ATMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28878591 | 0.92 | LMNA (0.31) | LMNAMAPTXBP1ATMSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28345647 | 0.90 | LMNA (0.30) | LMNAMAPTXBP1ATMSMN1; SMN2 | |
| Chloromethane SCHEMBL124970 | 0.90 | LMNA (0.30) | LMNAMAPTXBP1ATMSMN1; SMN2 | |
| Chloromethane SCHEMBL28391698 | 0.88 | — | — | |
| Methylamine SCHEMBL28885330 | 0.88 | SLC7A5 (0.33) | — | |
| Sulfuric Acid SCHEMBL10795901 | 0.86 | — | — | |
| Sulfuric Acid SCHEMBL28351011 | 0.84 | — | — | |
| SCHEMBL1155350 | 0.79 | — | — | |
| SCHEMBL9436752 | 0.78 | PPARD (0.37) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0924167-B1 | Amphoteric polymer/polyamine combinations for color removal and clarification of paper mill waste water | NALCO CHEMICAL CO (US) | 2003-09-03 | — | — | EP | disclosed |
| US-5961838-A | POLY(DIMETHYLAMINOETHYLACRYLATE METHYL CHLORIDE QUATERNARY SALT/ACRYLIC ACID); EPICHLOROHYDRIN-DIMETHYLAMINE POLYAMINE. | NALCO CHEMICAL COMPANY (US) | 1999-10-05 | — | — | US | disclosed |
| EP-0924167-A2 | Amphoteric polymer/polyamine combinations for color removal and clarification of paper mill waste water | NALCO CHEMICAL COMPANY (US) | 1999-06-23 | — | — | EP | disclosed |