SCHEMBL7095947

SCHEMBL7095947

O=C(O)c1c(Cl)c(Cl)c(Cl)c2c1C(=O)OC21c2ccc(O)cc2Oc2cc(O)cc(Cl)c21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
HPGD P15428 4/20 0.50
BRCA1 P38398 3/20 0.50
HSD17B10 Q99714 3/20 0.50
CYP2C9 P11712 2/20 0.50
ALOX15 P16050 2/20 0.50
ALOX12 P18054 2/20 0.50
FTO Q9C0B1 9/20 0.44
RECQL P46063 3/20 0.44
TDP1 Q9NUW8 3/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
SMAD3 P84022 2/20 0.44
BLM P54132 2/20 0.44
MAPT P10636 2/20 0.44
HTT P42858 2/20 0.44
CYP2C19 P33261 1/20 0.44
PRMT1 Q99873 1/20 0.44
ACE2 Q9BYF1 1/20 0.44
THRB P10828 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5142280 0.94 ALDH1A1 (0.50) ALDH1A1HPGDBRCA1HSD17B10CYP2C9
SCHEMBL202609 0.92 ALDH1A1 (0.50) ALDH1A1HPGDBRCA1HSD17B10CYP2C9
SCHEMBL6726589 0.87 ALDH1A1 (0.47) ALDH1A1HPGDBRCA1HSD17B10CYP2C9
SCHEMBL6884426 0.87 ALDH1A1 (0.45) ALDH1A1HPGDBRCA1HSD17B10CYP2C9
SCHEMBL534888 0.83 ALDH1A1 (0.52) ALDH1A1HPGDBRCA1HSD17B10CYP2C9
SCHEMBL5148271 0.83 ALDH1A1 (0.59) ALDH1A1HPGDBRCA1HSD17B10CYP2C9
SCHEMBL1032008 0.81 ALDH1A1 (0.59) ALDH1A1HPGDBRCA1HSD17B10CYP2C9
SCHEMBL213292 0.81 HPGD (0.53) ALDH1A1HPGDBRCA1HSD17B10CYP2C9
SCHEMBL134733 0.80 ALDH1A1 (0.63) ALDH1A1HPGDBRCA1HSD17B10CYP2C9
SCHEMBL30887311 0.80 ALDH1A1 (0.63) ALDH1A1HPGDBRCA1HSD17B10CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113509560-A Preparation method of ADAMTS13 enzyme specific activation type probe and application in diagnosis of malignant hematological diseases 苏州智影特生物医药技术有限公司 2021-10-19 CN claimed
CN-113509560-A Preparation method of ADAMTS13 enzyme specific activation type probe and application in diagnosis of malignant hematological diseases 苏州智影特生物医药技术有限公司 2021-10-19 CN disclosed
EP-2752496-B1 METHOD FOR DETECTING TOXIN-PRODUCING CLOSTRIDIUM DIFFICILE YAKULT HONSHA KK (JP) 2018-05-23 EP disclosed
US-9388474-B2 Method for detecting toxin-producing Clostridium difficile KABUSHIKI KAISHA YAKULT HONSHA (JP) 2016-07-12 US disclosed
CN-103764850-B The detection method of the generation clostridium difficile of toxin KABUSHIKI KAISHA YAKULT HONSHA (JP) 2015-11-25 CN disclosed
US-20140212879-A1 METHOD FOR DETECTING TOXIN-PRODUCING CLOSTRIDIUM DIFFICILE KABUSHIKI KAISHA YAKULT HONSHA (JP) 2014-07-31 US disclosed
EP-2752496-A1 METHOD FOR DETECTING TOXIN-PRODUCING CLOSTRIDIUM DIFFICILE Kabushiki Kaisha Yakult Honsha (JP) 2014-07-09 EP disclosed
CN-103764850-A Method for detecting toxin-producing clostridium difficile YAKULT HONSHA KK 2014-04-30 CN disclosed
EP-1312674-A1 Allosteric ribozymes and uses thereof Noxxon Pharma AG (DE) 2003-05-21 EP disclosed
US-20020137039-A1 5' Nuclease nucleic acid amplification assay having an improved internal control BAXTER AKTIENGESELLSCHAFT 2002-09-26 US disclosed
WO-2002052041-A2 5' NUCLEASE NUCLEIC ACID AMPLIFICATION ASSAY HAVING AN IMPROVED INTERNAL CONTROL BAXTER AKTIENGESELLSCHAFT (AT) 2002-07-04 WO disclosed