SCHEMBL534888

SCHEMBL534888

O=C(O)c1cc(O)cc2c1C1(OC(=O)c3c(Cl)c(Cl)c(Cl)c(Cl)c31)c1ccc(O)cc1O2

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.52
HPGD P15428 3/20 0.52
BRCA1 P38398 3/20 0.52
HSD17B10 Q99714 3/20 0.52
CYP2C9 P11712 1/20 0.52
ALOX15 P16050 1/20 0.52
ALOX12 P18054 1/20 0.52
SMAD3 P84022 2/20 0.47
FTO Q9C0B1 9/20 0.46
TDP1 Q9NUW8 4/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
RECQL P46063 3/20 0.46
BLM P54132 2/20 0.46
MAPT P10636 2/20 0.46
HTT P42858 2/20 0.46
CYP2C19 P33261 1/20 0.46
PRMT1 Q99873 1/20 0.46
ACE2 Q9BYF1 1/20 0.46
THRB P10828 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30887311 0.86 ALDH1A1 (0.63) ALDH1A1HPGDBRCA1HSD17B10CYP2C9
SCHEMBL30887310 0.86 ALDH1A1 (0.63) ALDH1A1HPGDBRCA1HSD17B10CYP2C9
SCHEMBL29361906 0.86 ALDH1A1 (0.63) ALDH1A1HPGDBRCA1HSD17B10CYP2C9
SCHEMBL134733 0.86 ALDH1A1 (0.63) ALDH1A1HPGDBRCA1HSD17B10CYP2C9
SCHEMBL5453230 0.85 ALDH1A1 (0.62) ALDH1A1HPGDBRCA1HSD17B10CYP2C9
SCHEMBL6535975 0.85 HPGD (0.51) ALDH1A1HPGDBRCA1HSD17B10CYP2C9
SCHEMBL161170 0.84 SMAD3 (0.54) ALDH1A1HPGDBRCA1HSD17B10CYP2C9
SCHEMBL5142280 0.83 ALDH1A1 (0.50) ALDH1A1HPGDBRCA1HSD17B10CYP2C9
SCHEMBL7095947 0.83 ALDH1A1 (0.50) ALDH1A1HPGDBRCA1HSD17B10CYP2C9
SCHEMBL202609 0.83 ALDH1A1 (0.50) ALDH1A1HPGDBRCA1HSD17B10CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 342 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024152018-A2 SYSTEMS AND METHODS FOR LIBRARY PREPARATION ADAPTERS ULTIMA GENOMICS, INC. (US) 2024-07-18 WO disclosed
US-12031180-B2 Methods, devices, and systems for analyte detection and analysis ULTIMA GENOMICS, INC. (US) 2024-07-09 US disclosed
WO-2024137873-A1 QUANTIFICATION OF CO-LOCALIZED TAG SEQUENCES USING ORTHOGONAL SEQUENCE ENCODING ULTIMA GENOMICS, INC. (US) 2024-06-27 WO disclosed
EP-4388129-A2 SYSTEMS AND METHODS FOR SAMPLE PREPARATION FOR SEQUENCING Ultima Genomics, Inc. (US) 2024-06-26 EP disclosed
US-20240167080-A1 METHODS FOR NUCLEIC ACID DETECTION ULTIMA GENOMICS, INC. 2024-05-23 US disclosed
EP-4368727-A2 METHODS AND SYSTEMS FOR ANALYTE DETECTION AND ANALYSIS Ultima Genomics, Inc. (US) 2024-05-15 EP disclosed
US-20240132955-A1 BENIGN SCAR-FORMING CLEAVABLE LINKERS ULTIMA GENOMICS, INC. 2024-04-25 US disclosed
US-20240124856-A1 METHODS FOR PRODUCING MODIFIED REVERSE TRANSCRIPTASES BIO-RAD LABORATORIES, INC. 2024-04-18 US disclosed
US-11951478-B2 Microfluidic siphoning array for nucleic acid quantification COMBINATI INCORPORATED (US) 2024-04-09 US disclosed
US-11946097-B2 Linkers and methods for optical detection and sequencing ULTIMA GENOMICS, INC. (US) 2024-04-02 US disclosed
US-20040224317-A1 Systems and methods for fluorescence detection with a movable detection module MJ RESEARCH (US) 2004-11-11 US disclosed
EP-1352091-A4 COMPOSITIONS AND METHODS ENABLING A TOTALLY INTERNALLY CONTROLLED AMPLIFICATION REACTION CEPHEID (US) 2004-07-21 EP disclosed
EP-1415152-A2 METHODS, APPARATUS, AND COMPUTER PROGRAMS FOR VERIFYING THE INTEGRITY OF A PROBE Cepheid (US) 2004-05-06 EP disclosed
EP-1352091-A2 COMPOSITIONS AND METHODS ENABLING A TOTALLY INTERNALLY CONTROLLED AMPLIFICATION REACTION Cepheid (US) 2003-10-15 EP disclosed
US-20030064368-A1 Methods, apparatus, and computer programs for verifying the integrity of a probe CEPHEID 2003-04-03 US disclosed
US-6534645-B2 Amplifying preferential nucleotide sequences; obtain nucleotide sequences, incubate primers and probes, amplify, measure binding of the target probe CEPHEID 2003-03-18 US disclosed
WO-2003009100-A2 METHODS, APPARATUSES, AND COMPUTER PROGRAMS FOR VERIFYING THE INTEGRITY OF A PROBE CEPHEID (US) 2003-01-30 WO disclosed
US-20020119464-A1 Compositions and methods enabling a totally internally controlled amplification reaction MCMILLAN WILLIAM A (US) 2002-08-29 US disclosed
WO-2002052030-A2 COMPOSITIONS AND METHODS ENABLING A TOTALLY INTERNALLY CONTROLLED AMPLIFICATION REACTION CEPHEID (US) 2002-07-04 WO disclosed
US-6312929-B1 AMPLIFYING PREFERENTIAL NUCLEOTIDE SEQUENCES; MIX PROBES, PRIMER AND NUCLEOTIDE SEQUENCES IN SOLUTION, AMPLIFY NUCLEOTIDE SEQUENCES, MONITOR BINDING OF PROBE CEPHEID 2001-11-06 US disclosed