Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | CA12 | O43570 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13889053 | 0.95 | MEN1 (0.63) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL14539074 | 0.92 | MEN1 (0.78) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL812658 | 0.88 | USP2 (0.69) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL5567042 | 0.84 | ALDH1A1 (0.75) | MEN1KMT2ARAB9AALDH1A1HTT | |
| SCHEMBL19392344 | 0.84 | ALDH1A1 (0.61) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL8213969 | 0.82 | ALDH1A1 (0.72) | MEN1KMT2ARAB9AALDH1A1HTT | |
| SCHEMBL812683 | 0.81 | ALDH1A1 (0.75) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL4514521 | 0.81 | TAAR1 (0.61) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL16265376 | 0.80 | LMNA (0.66) | MEN1KMT2ARAB9AALDH1A1CYP1A2 | |
| SCHEMBL7937849 | 0.79 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082777-A2 | NOVEL GLUCOCORTICOID RECEPTOR LIGANDS | KARO BIO AB (SE) | 2003-10-09 | — | — | WO | disclosed |