Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 19/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 12/20 | 0.55 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7516391 | 0.90 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL7512087 | 0.83 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL6704426 | 0.76 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL5210454 | 0.74 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL7486750 | 0.71 | PTGS2 (0.77) | PTGS2PTGS1 | |
| SCHEMBL29671475 | 0.71 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL4575852 | 0.71 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL6401652 | 0.68 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL5210752 | 0.68 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL5205556 | 0.68 | PTGS2 (0.49) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040242637-A1 | Tyrosine kinase inhibitors | HARTMAN GEORGE D (US) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242637-A1 | Tyrosine kinase inhibitors | ERBB2, TYRO3, TIE1 | PTGS2 983/4885PTGS1 791/4885SOS1 1044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.