Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096039 | 0.90 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL7512087 | 0.81 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL7486750 | 0.81 | PTGS2 (0.77) | PTGS2PTGS1 | |
| SCHEMBL6704426 | 0.72 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL5202732 | 0.72 | PTGS2 (0.73) | PTGS2PTGS1 | |
| SCHEMBL6401652 | 0.71 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL5210752 | 0.70 | PTGS2 (0.71) | PTGS2PTGS1 | |
| SCHEMBL5205556 | 0.70 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL5140758 | 0.70 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL5210454 | 0.68 | PTGS2 (0.50) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863891-B1 | (METHYLSULFONYL)PHENYL-2-(5H)-FURANONES AS COX-2 INHIBITORS | MERCK FROSST CANADA INC (CA) | 2002-12-11 | — | — | EP | claimed |
| US-6169188-B1 | TREATING CYCLOOXYGENASE-2 MEDIATED DISEASES | MERCK FROSST CANADA & CO. (CA) | 2001-01-02 | — | — | US | disclosed |