Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.68 |
| ▸ | JAK2 | O60674 | 1/20 | 0.68 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | GPX4 | P36969 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.47 |
| ▸ | ICMT | O60725 | 1/20 | 0.46 |
| ▸ | ALB | P02768 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6424475 | 1.00 | NPC1 (0.68) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL4024848 | 1.00 | NPC1 (0.68) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL11344801 | 1.00 | NPC1 (0.68) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL1082836 | 1.00 | NPC1 (0.68) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL11344796 | 1.00 | NPC1 (0.68) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL3055011 | 0.98 | NPC1 (0.65) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL1506356 | 0.93 | NPC1 (0.58) | NPC1RAB9APAX8JAK2TP53 | |
| Hydrochloric Acid SCHEMBL27532672 | 0.92 | NPC1 (0.56) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL10960608 | 0.86 | NPC1 (0.71) | NPC1RAB9APAX8JAK2TP53 | |
| SCHEMBL10961189 | 0.86 | NPC1 (0.71) | NPC1RAB9APAX8JAK2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6320862-A | — | — | None | — | — | JP | disclosed |
| EP-2050790-B1 | BIODEGRADABLE RESIN COMPOSITION AND MOLDED BODY THEREOF | KANEKA CORP (JP) | 2018-06-13 | — | — | EP | disclosed |
| US-6605618-B2 | Antidiabetic agents; hypoglycemic agents; anticholesterol agents; side effect reduction | WYETH | 2003-08-12 | — | — | US | disclosed |
| US-20030018045-A1 | Heterocyclic beta-3 adrenergic receptor agonists | WYETH (US) | 2003-01-23 | — | — | US | disclosed |
| EP-0849630-B1 | Process for producing color filter | FUJI PHOTO FILM CO LTD (JP) | 2001-11-21 | — | — | EP | disclosed |
| EP-0849630-A2 | Process for producing color filter | FUJI PHOTO FILM CO., LTD. (JP) | 1998-06-24 | — | — | EP | disclosed |
| JP-H06320862-A | REVERSIBLE THERMAL RECORDING MATERIAL | MITSUBISHI PAPER MILLS LTD | 1994-11-22 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018045-A1 | Heterocyclic beta-3 adrenergic receptor agonists | ADRB2, ADRB1, ADRB3 | NPC1 1172/4885RAB9A 1800/4885PAX8 4565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.