SCHEMBL7096448

SCHEMBL7096448

CCN1C(=O)C(N=O)=C(N)N2NN(COCc3ccc(OC)cc3)C=C12

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 2/20 0.32
GSK3B P49841 2/20 0.32
CMA1 P23946 1/20 0.31
IDO1 P14902 1/20 0.30
AGXT P21549 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34413 0.57 IDO1 (0.67) IDO1AGXT
SCHEMBL2618879 0.56 IDO1 (0.59) IDO1AGXT
SCHEMBL1475481 0.56 IDO1 (0.64) IDO1AGXT
Hydrochloric Acid SCHEMBL28912134 0.56 IDO1 (0.68) IDO1AGXT
Bromide SCHEMBL28558295 0.56 IDO1 (0.64) IDO1AGXT
Methoxymethane SCHEMBL28823290 0.56 IDO1 (0.64) IDO1AGXT
Potassium SCHEMBL1477050 0.56 IDO1 (0.64) IDO1AGXT
SCHEMBL13296351 0.56 CMA1 (0.74) GSK3AGSK3BCMA1KDM4E
SCHEMBL12502488 0.56 TDP1 (0.54) CMA1IDO1AGXT
SCHEMBL28386429 0.55 IDO1 (0.63) IDO1AGXT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1087973-B1 IMIDAZOTRIAZOLOPYRIMIDINES USED AS A DRUG HAVING AN ADENOSINE ANTAGONIST ACTIVITY BOEHRINGER INGELHEIM PHARMA (DE) 2003-01-08 EP disclosed