Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKLR | P30613 | 6/20 | 0.71 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.64 |
| ▸ | BCL2 | P10415 | 3/20 | 0.64 |
| ▸ | TTR | P02766 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | PGAM1 | P18669 | 5/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11411791 | 0.81 | FTO (0.73) | PKLRMCL1BCL2TTRALDH1A1 | |
| SCHEMBL8996447 | 0.79 | MAPT (0.66) | PKLRMCL1BCL2TTRALDH1A1 | |
| SCHEMBL68338 | 0.79 | TTR (0.64) | MCL1BCL2TTRALDH1A1L3MBTL1 | |
| SCHEMBL555230 | 0.78 | BCL2 (1.00) | PKLRMCL1BCL2TTRALDH1A1 | |
| SCHEMBL29388375 | 0.78 | BCL2 (1.00) | PKLRMCL1BCL2TTRALDH1A1 | |
| SCHEMBL29384381 | 0.78 | BCL2 (1.00) | PKLRMCL1BCL2TTRALDH1A1 | |
| SCHEMBL6548219 | 0.78 | BCL2 (0.67) | PKLRMCL1BCL2TTRALDH1A1 | |
| SCHEMBL29407198 | 0.78 | BCL2 (0.67) | PKLRMCL1BCL2TTRALDH1A1 | |
| Calcium SCHEMBL29860211 | 0.77 | TTR (0.62) | MCL1BCL2TTRALDH1A1L3MBTL1 | |
| SCHEMBL28550294 | 0.77 | TTR (0.62) | MCL1BCL2TTRALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003089576-A2 | ANTICANCER ANTHRAQUINONES AND METHOD OF USE THEREOF | MICHIGAN STATE UNIVERSITY (US) | 2003-10-30 | — | — | WO | disclosed |