SCHEMBL8996447

SCHEMBL8996447

O=C(O)c1cc(O)c2c(c1O)C(=O)c1ccccc1C2=O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.66
MEN1 O00255 6/20 0.66
KMT2A Q03164 6/20 0.66
ALDH1A1 P00352 5/20 0.66
MAPK1 P28482 4/20 0.66
MAOA P21397 3/20 0.66
KDM4E B2RXH2 3/20 0.66
RECQL P46063 3/20 0.66
HPGD P15428 3/20 0.66
L3MBTL1 Q9Y468 2/20 0.66
TTR P02766 2/20 0.66
CYP3A4 P08684 2/20 0.66
ALOX15 P16050 2/20 0.66
ALOX12 P18054 2/20 0.66
DAPK1 P53355 2/20 0.66
CYP1B1 Q16678 2/20 0.66
HSD17B10 Q99714 2/20 0.66
TDP1 Q9NUW8 2/20 0.66
CYP1A1 P04798 1/20 0.66
HSPD1 P10809 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8996324 0.87 FTO (0.68) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL8996538 0.84 FTO (0.50) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL23522461 0.83 TTR (0.56) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL29377086 0.83 MAPT (0.51) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL11876497 0.83 MAPT (0.74) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL11212448 0.83 MAPT (0.74) MAPTMEN1KMT2AALDH1A1MAPK1
Purpurin SCHEMBL33871 0.80 MEN1 (1.00) MAPTMEN1KMT2AALDH1A1MAPK1
Purpurin SCHEMBL29539242 0.80 MEN1 (1.00) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL14304679 0.80 MEN1 (0.78) MAPTMEN1KMT2AALDH1A1MAPK1
Purpurin SCHEMBL29429206 0.80 MEN1 (1.00) MAPTMEN1KMT2AALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-56043210-A None JP disclosed
US-11841339-B2 Voltammetric reference control system ANB SENSORS LTD (GB) 2023-12-12 US disclosed
US-11841339-B2 Voltammetric reference control system ANB SENSORS LTD (GB) 2023-12-12 US disclosed
US-11674921-B2 Online reference calibration ANB SENSORS LTD (GB) 2023-06-13 US disclosed
US-11674921-B2 Online reference calibration ANB SENSORS LTD (GB) 2023-06-13 US disclosed
US-11307168-B2 Online reference calibration ANB SENSORS LIMITED (GB) 2022-04-19 US disclosed
US-20210223197-A1 REFERENCE ELECTRODE USING LOCAL ENVIRONMENT PH CONTROL ANB SENSORS LIMITED (GB) 2021-07-22 US disclosed
US-20200264131-A1 ONLINE REFERENCE CALIBRATION ANB SENSORS LIMITED (GB) 2020-08-20 US disclosed
US-20190293592-A1 REFERENCE ELECTRODE USING LOCAL ENVIRONMENT PH CONTROL ANB SENSORS LIMITED (GB) 2019-09-26 US disclosed
WO-2019073002-A1 ONLINE REFERENCE CALIBRATION ANB SENSORS LIMITED (GB) 2019-04-18 WO disclosed
WO-2019072991-A1 VOLTAMMETRIC REFERENCE CONTROL SYSTEM ANB SENSORS LIMITED (GB) 2019-04-18 WO disclosed
WO-2017208029-A1 REFERENCE ELECTRODE USING LOCAL ENVIRONMENT pH CONTROL ANB SENSORS LIMITED (GB) 2017-12-07 WO disclosed
US-5480873-A ARTHRITIS LILLY INDUSTRIES LIMITED (GB) 1996-01-02 US disclosed
CN-1079732-A Medical compounds LILLY INDUSTRIES LTD (GB) 1993-12-22 CN disclosed
EP-0570091-A1 Anthraquinone derivatives, process for their preparation and their use as medicaments LILLY INDUSTRIES LIMITED (GB) 1993-11-18 EP disclosed
JP-S5643210-A IMMUNITY ENHANCING, DRUG RESISTANCE PREVENTIVE AND CARCINOSTATIC AGENT HAYASHI KOUTAKU 1981-04-21 JP disclosed
US-3964862-A Process for dyeing and printing textile materials of synthetic organic fibers CIBA-GEIGY AG (CH) 1976-06-22 US disclosed