Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | PLD2 | O14939 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096725 | 1.00 | PTPN1 (0.58) | PTPN1KDM4EHSD17B10HPGDSCN4A | |
| SCHEMBL5797581 | 0.91 | PTPN1 (0.60) | PTPN1KDM4EHSD17B10HPGDSCN4A | |
| SCHEMBL5797661 | 0.86 | PTPN1 (0.45) | PTPN1RAB9A | |
| SCHEMBL7091991 | 0.83 | PTPN1 (0.42) | PTPN1KDM4EHSD17B10HPGDALDH1A1 | |
| SCHEMBL5767679 | 0.83 | PTPN1 (0.81) | PTPN1KDM4EHSD17B10HPGDSCN4A | |
| SCHEMBL5769149 | 0.83 | PTPN1 (0.81) | PTPN1KDM4EHSD17B10HPGDSCN4A | |
| SCHEMBL5810837 | 0.82 | RAB9A (0.51) | PTPN1HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL5810842 | 0.82 | RAB9A (0.51) | PTPN1HPGDALDH1A1NPC1RAB9A | |
| SCHEMBL7698367 | 0.82 | KDM4E (0.50) | PTPN1KDM4EHSD17B10HPGDSCN4A | |
| SCHEMBL7699527 | 0.82 | KDM4E (0.50) | PTPN1KDM4EHSD17B10HPGDSCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301516-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2003-04-16 | — | — | EP | disclosed |