Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SCN4A | P35499 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
| ▸ | PLD2 | O14939 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7699527 | 1.00 | KDM4E (0.50) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL7855442 | 0.87 | KDM4E (0.55) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL7701502 | 0.86 | HPGD (0.43) | KDM4EHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL7699460 | 0.85 | NPC1 (0.48) | KDM4EHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL7694099 | 0.85 | KDM4E (0.49) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL7694101 | 0.85 | KDM4E (0.49) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL7575384 | 0.84 | POLB (0.36) | KDM4EHSD17B10HPGDALDH1A1NPC1 | |
| SCHEMBL7700382 | 0.83 | ALDH1A1 (0.37) | KDM4EHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL7521793 | 0.83 | PTPN1 (0.53) | KDM4EHSD17B10HPGDSCN4ASCN9A | |
| SCHEMBL7524247 | 0.83 | PTPN1 (0.53) | KDM4EHSD17B10HPGDSCN4ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002004458-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2002-01-17 | — | — | WO | claimed |
| WO-2002004458-A1 | MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPASES) | NOVO NORDISK A/S (DK) | 2002-01-17 | — | — | WO | disclosed |