Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | TDO2 | P48775 | 3/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28103272 | 0.87 | KCNH2 (0.40) | KCNH2IDO1TDO2 | |
| SCHEMBL729527 | 0.84 | NOTUM (0.51) | — | |
| SCHEMBL31587177 | 0.81 | NOTUM (0.47) | KMT2AKCNH2BRD9RXRAGRIN1 | |
| SCHEMBL20250029 | 0.80 | CA12 (0.42) | KMT2AKCNH2BRD9KAT2BPIN1 | |
| SCHEMBL16201986 | 0.80 | KCNH2 (0.46) | KMT2AKCNH2BRD9ALDH1A1KAT2B | |
| SCHEMBL12967879 | 0.80 | NPC1 (0.43) | KMT2AALDH1A1POLBMEN1GAA | |
| SCHEMBL31587364 | 0.78 | KMT2A (0.46) | KMT2ABRD9ALDH1A1KAT2BPIN1 | |
| SCHEMBL2384190 | 0.78 | ALDH1A1 (0.47) | KMT2AALDH1A1CYP1A2GAAMAPT | |
| SCHEMBL31587119 | 0.78 | KCNH2 (0.47) | KMT2AKCNH2BRD9KAT2BPIN1 | |
| SCHEMBL12789222 | 0.77 | KDM1A (0.41) | ALDH1A1POLBCYP1A2GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946514-B1 | METHOD FOR PRODUCING N-SUBSTITUTED 3-HYDROXYPYRAZOLES | BASF AG (DE) | 2003-05-02 | — | — | EP | disclosed |
| CN-1098253-C | Process for preparing N-substituted 3-hydroxypyrazoles | BASF AG (DE) | 2003-01-08 | — | — | CN | disclosed |
| US-6040458-A | Method for producing N-substituted 3-hydroxypyrazoles | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-21 | — | — | US | disclosed |
| CN-1240433-A | Process for preparing N-substituted 3-hydroxypyrazoles | BASF AG (DE) | 2000-01-05 | — | — | CN | disclosed |
| EP-0946514-A1 | METHOD FOR PRODUCING N-SUBSTITUTED 3-HYDROXYPYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998027062-A1 | METHOD FOR PRODUCING N-SUBSTITUTED 3-HYDROXYPYRAZOLES | BASF AKTIENGESELLSCHAFT (DE) | 1998-06-25 | — | — | WO | disclosed |