SCHEMBL16201986

SCHEMBL16201986

Cc1ccn(-c2ccc(F)c(Cl)c2)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 4/20 0.46
BRD9 Q9H8M2 2/20 0.46
KAT6A Q92794 1/20 0.44
KMT2A Q03164 1/20 0.44
HTT P42858 1/20 0.44
RXRA P19793 2/20 0.42
GRIN1 Q05586 2/20 0.42
GRIN2B Q13224 2/20 0.42
AVPR2 P30518 3/20 0.42
MAPT P10636 2/20 0.42
RAB9A P51151 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
GAA P10253 1/20 0.42
OXTR P30559 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
AVPR1A P37288 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
KAT2B Q92831 2/20 0.40
PIN1 Q13526 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16202096 0.87 KCNH2 (0.46) KCNH2KAT6AHTTAVPR2MAPT
SCHEMBL2615992 0.84 NOTUM (0.51) HTTAVPR2MAPTRAB9AKDM4E
SCHEMBL25735722 0.83 AVPR2 (0.46) KMT2AHTTAVPR2MAPTRAB9A
SCHEMBL16201985 0.83 KAT6A (0.46) KCNH2KAT6AHTTRXRAGRIN1
SCHEMBL16911272 0.80 RAB9A (0.54) KAT6AHTTAVPR2MAPTRAB9A
SCHEMBL20250029 0.80 CA12 (0.42) KCNH2BRD9KMT2ARXRAGRIN1
SCHEMBL15056904 0.80 RXRA (0.45) KAT6AHTTRXRAGRIN1GRIN2B
SCHEMBL15056697 0.80 RAB9A (0.54) KAT6AHTTAVPR2MAPTRAB9A
SCHEMBL17720573 0.80 HTT (0.44) HTTAVPR2MAPTRAB9AKDM4E
SCHEMBL7096905 0.80 KMT2A (0.41) KCNH2BRD9KMT2ARXRAGRIN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160249615-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors BASF SE (DE) 2016-09-01 US disclosed
US-20160145219-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2016-05-26 US disclosed
US-20160145202-A1 Strobilurin Type Compounds for Combating Phytopathogenic Fungi BASF SE (DE) 2016-05-26 US disclosed
US-20160122327-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2016-05-05 US disclosed
US-9271501-B2 Use of strobilurin type compounds for combating phytopathogenic fungi resistant to QO inhibitors BASF SE (DE) 2016-03-01 US disclosed
US-20140323305-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors BASF SE (DE) 2014-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160122327-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI SNX1, DPM1, SNU13 KCNH2 3747/4885BRD9 2533/4885KAT6A 4678/4885
US-20160145219-A1 STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI DPM1, CROCC, SNX1 KCNH2 4214/4885BRD9 1543/4885KAT6A 4479/4885
US-20160145202-A1 Strobilurin Type Compounds for Combating Phytopathogenic Fungi DPM1, CROCC, SNX1 KCNH2 4214/4885BRD9 1543/4885KAT6A 4479/4885
US-20140323305-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors SQOR, COX5B, UQCRB KCNH2 1781/4885BRD9 2686/4885KAT6A 4357/4885
US-20160249615-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors SQOR, COX5B, UQCRB KCNH2 1781/4885BRD9 2686/4885KAT6A 4357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.