Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | HMGCR | P04035 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.33 |
| ▸ | ALB | P02768 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2683316 | 0.79 | GABRA1 (0.52) | GABRA1GABRB2PTGS2PTGS1LMNA | |
| SCHEMBL27839278 | 0.79 | HSPA5 (0.43) | HMGCRLMNACYP2C9TSHRNFKB1 | |
| SCHEMBL21260712 | 0.78 | GABRA1 (0.42) | GABRA1GABRB2PTGS2PTGS1LMNA | |
| SCHEMBL2557215 | 0.78 | GABRA1 (0.59) | GABRA1GABRB2HMGCRPTGS2LMNA | |
| SCHEMBL13863080 | 0.76 | GABRA1 (0.41) | GABRA1GABRB2LMNAHTR2AMEN1 | |
| SCHEMBL22243486 | 0.74 | PNMT (0.46) | GABRA1GABRB2PTGS2PTGS1LMNA | |
| SCHEMBL20754706 | 0.74 | GABRA1 (0.42) | GABRA1GABRB2PTGS2PTGS1LMNA | |
| SCHEMBL5165556 | 0.74 | GABRA1 (0.55) | GABRA1GABRB2PTGS2LMNACYP2C9 | |
| SCHEMBL18701030 | 0.74 | GABRA1 (0.42) | GABRA1GABRB2PTGS2PTGS1LMNA | |
| SCHEMBL39082 | 0.71 | HMGCR (0.57) | HMGCRLMNACYP2C9TSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070037-B1 | ANTI-INFLAMMATORY, ANTIBACTERIAL BENZYL PHENOL AGENTS | COLGATE PALMOLIVE CO (US) | 2003-08-20 | — | — | EP | claimed |