SCHEMBL7097200

SCHEMBL7097200

NC(COC1CCCCO1)Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.43
KDM4C Q9H3R0 1/20 0.41
SCN4A P35499 3/20 0.40
ANPEP P15144 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TACR1 P25103 1/20 0.39
DHFR P00374 1/20 0.35
ROCK2 O75116 1/20 0.35
ROCK1 Q13464 1/20 0.35
MMP2 P08253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17846160 0.83 MEN1 (0.41) KDM4CMEN1KMT2A
SCHEMBL10433383 0.81 KDM4C (0.39) KDM4CMEN1KMT2ATACR1DHFR
SCHEMBL7098095 0.81 KDM4C (0.39) KDM4CMEN1KMT2ATACR1DHFR
SCHEMBL7330307 0.80 MEN1 (0.39) KDM4CMEN1KMT2A
SCHEMBL10433401 0.80 KDM4C (0.39) KDM4CMEN1KMT2ADHFR
SCHEMBL30781642 0.78 KDM4C (0.42) KDM4CMEN1KMT2ADHFR
SCHEMBL10433458 0.78 CREBBP (0.37) KDM4CMEN1KMT2ATACR1
SCHEMBL10433460 0.78 CREBBP (0.37) KDM4CMEN1KMT2ATACR1
SCHEMBL4184332 0.77 KDM4C (0.47) KDM4CMEN1KMT2ATACR1
SCHEMBL10433363 0.77 EPHX1 (0.51) EPHX1KDM4CMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1140952-B1 ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION BIOAGENCY AG (DE) 2003-09-03 EP disclosed
EP-1140952-A1 ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION Jomaa Pharmaka GmbH (DE) 2001-10-10 EP disclosed
WO-2000037477-A1 ORGANO-PHOSPHORUS COMPOUNDS AND THEIR UTILIZATION JOMAA PHARMAKA GMBH (DE) 2000-06-29 WO disclosed