Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320247 | 0.83 | KDM4C (0.36) | MEN1KMT2AKDM4CSLC6A3ALDH1A1 | |
| SCHEMBL17846160 | 0.83 | MEN1 (0.41) | MEN1KMT2AKDM4CSLC6A3ALDH1A1 | |
| SCHEMBL10433460 | 0.82 | CREBBP (0.37) | MEN1KMT2AKDM4CSLC6A3ITGB1 | |
| SCHEMBL10433458 | 0.82 | CREBBP (0.37) | MEN1KMT2AKDM4CSLC6A3ITGB1 | |
| SCHEMBL10433363 | 0.81 | EPHX1 (0.51) | MEN1KMT2AKDM4CSLC6A3ITGB1 | |
| SCHEMBL7097200 | 0.80 | EPHX1 (0.43) | MEN1KMT2AKDM4C | |
| SCHEMBL3993157 | 0.79 | ALDH1A1 (0.38) | MEN1KMT2AKDM4CSLC6A3ALDH1A1 | |
| SCHEMBL10433383 | 0.78 | KDM4C (0.39) | MEN1KMT2AKDM4CSLC6A3ALDH1A1 | |
| SCHEMBL7098095 | 0.78 | KDM4C (0.39) | MEN1KMT2AKDM4CSLC6A3ALDH1A1 | |
| SCHEMBL9184517 | 0.77 | SIGMAR1 (0.36) | MEN1KMT2AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0353732-A2 | Fluoro-olefins, method for their preparation and their use | CIBA-GEIGY AG (CH) | 1990-02-07 | — | — | EP | disclosed |
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |