Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 3/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099974 | 0.89 | HCAR2 (0.33) | ALDH1A1TSHRCA1CA2HCAR2 | |
| SCHEMBL7101062 | 0.81 | ALDH1A1 (0.38) | ALDH1A1HPGDNPSR1NPC1LMNA | |
| SCHEMBL6747488 | 0.80 | ALDH1A1 (0.58) | ALDH1A1ATMTSHRHPGDNPSR1 | |
| SCHEMBL6117887 | 0.76 | ALDH1A1 (0.48) | ALDH1A1ATMTSHRHPGDNPSR1 | |
| SCHEMBL3108668 | 0.75 | ALDH1A1 (0.52) | ALDH1A1ATMTSHRHPGDNPSR1 | |
| SCHEMBL16160733 | 0.75 | ALDH1A1 (0.52) | ALDH1A1ATMTSHRHPGDCA1 | |
| SCHEMBL10595821 | 0.75 | ALDH1A1 (0.58) | ALDH1A1ATMTSHRHPGDNPSR1 | |
| SCHEMBL7102211 | 0.74 | ALDH1A1 (0.47) | ALDH1A1ATMTSHRHPGDNPSR1 | |
| SCHEMBL803629 | 0.73 | ALDH1A1 (0.50) | ALDH1A1ATMTSHRHPGDNPSR1 | |
| SCHEMBL28924651 | 0.73 | ALDH1A1 (0.50) | ALDH1A1ATMTSHRHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038861-B1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6593488-B1 | Reacting 2-fluorocarboxylate with carboxylate | UBE INDUSTRIES, LTD. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-1038861-A1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES LIMITED (JP) | 2000-09-27 | — | — | EP | disclosed |