Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19024090 | 0.88 | ALDH1A1 (0.41) | ALDH1A1HPGDMMP8LMNAHSD17B10 | |
| SCHEMBL196658 | 0.85 | ALDH1A1 (0.39) | ALDH1A1HPGDMMP8LMNAHSD17B10 | |
| SCHEMBL23473944 | 0.85 | ALDH1A1 (0.39) | ALDH1A1HPGDMMP8LMNAHSD17B10 | |
| SCHEMBL7099974 | 0.84 | HCAR2 (0.33) | ALDH1A1LMNA | |
| SCHEMBL2319054 | 0.83 | ALDH1A1 (0.40) | ALDH1A1HPGDMMP8LMNAHSD17B10 | |
| SCHEMBL7095855 | 0.82 | TSHR (0.39) | ALDH1A1GAA | |
| SCHEMBL7097266 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HPGDLMNANPC1NPSR1 | |
| SCHEMBL7096487 | 0.78 | SMN1; SMN2 (0.38) | ALDH1A1HPGD | |
| SCHEMBL7096502 | 0.77 | TSHR (0.37) | — | |
| SCHEMBL141446 | 0.77 | ALDH1A1 (0.53) | ALDH1A1HPGDMMP8LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038861-B1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6593488-B1 | Reacting 2-fluorocarboxylate with carboxylate | UBE INDUSTRIES, LTD. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-1038861-A1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES LIMITED (JP) | 2000-09-27 | — | — | EP | disclosed |