Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | EPOR | P19235 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101078 | 0.85 | — | — | |
| SCHEMBL7096890 | 0.80 | TDP1 (0.30) | TDP1 | |
| SCHEMBL7097275 | 0.79 | — | — | |
| SCHEMBL6431287 | 0.78 | FDPS (0.39) | TDP1SMN1; SMN2EPORSLC22A6 | |
| SCHEMBL28466576 | 0.78 | FDPS (0.39) | TDP1SMN1; SMN2EPORSLC22A6 | |
| SCHEMBL4998502 | 0.75 | FOLH1 (0.41) | TDP1SMN1; SMN2EPORSLC22A6 | |
| SCHEMBL2450587 | 0.75 | TDP1 (0.39) | TDP1SMN1; SMN2EPORSLC22A6 | |
| SCHEMBL8657775 | 0.74 | GABRR1 (0.38) | TDP1SMN1; SMN2EPORSLC22A6 | |
| Hydrochloric Acid SCHEMBL3914766 | 0.73 | GPR84 (0.40) | TDP1SLC22A6 | |
| SCHEMBL1172848 | 0.73 | TDP1 (0.40) | TDP1SMN1; SMN2EPORSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140795-B1 | N-3, 3-DIMETHYLBUTYL-L-ASPARTIC ACID AND ESTERS THEREOF, THE PROCESS OF PREPARING THE SAME, AND THE PROCESS FOR PREPARING N-[N-(3,3-DIMETHYLBUTYL)-L-ALPHA-ASPARTYL)-L-PHENYLALANINE-1-METHYLESTER THEREFROM | NUTRASWEET CO (US) | 2003-09-03 | — | — | EP | claimed |
| US-6077962-A | N-3, 3-dimethylbutyl-L-aspartic acid and esters thereof, the process of preparing the same, and the process for preparing N-(N-(3,3-dimethylbutyl) -α L-aspartyl)-L- phenylalanine 1-methyl ester therefrom | THE NUTRASWEET COMPANY (US) | 2000-06-20 | — | — | US | claimed |
| EP-1140795-B1 | N-3, 3-DIMETHYLBUTYL-L-ASPARTIC ACID AND ESTERS THEREOF, THE PROCESS OF PREPARING THE SAME, AND THE PROCESS FOR PREPARING N-[N-(3,3-DIMETHYLBUTYL)-L-ALPHA-ASPARTYL)-L-PHENYLALANINE-1-METHYLESTER THEREFROM | NUTRASWEET CO (US) | 2003-09-03 | — | — | EP | disclosed |
| EP-1140795-A1 | N-3, 3-DIMETHYLBUTYL-L-ASPARTIC ACID AND ESTERS THEREOF, THE PROCESS OF PREPARING THE SAME, AND THE PROCESS FOR PREPARING N-[N-(3,3-DIMETHYLBUTYL)-L-ALPHA-ASPARTYL)-L-PHENYLALANINE-1-METHYLESTER THEREFROM | The NutraSweet Company (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039075-A1 | N-3, 3-DIMETHYLBUTYL-L-ASPARTIC ACID AND ESTERS THEREOF, THE PROCESS OF PREPARING THE SAME, AND THE PROCESS FOR PREPARING N-[N-(3, 3-DIMENTHYLBUTYL)-L-α-ASPARTYL]-L-PHENYLALANINE 1-METHYL ESTER THEREFROM | THE NUTRASWEET COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |
| US-6077962-A | N-3, 3-dimethylbutyl-L-aspartic acid and esters thereof, the process of preparing the same, and the process for preparing N-(N-(3,3-dimethylbutyl) -α L-aspartyl)-L- phenylalanine 1-methyl ester therefrom | THE NUTRASWEET COMPANY (US) | 2000-06-20 | — | — | US | disclosed |