Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5209634 | 0.80 | KMT2A (0.51) | KMT2AMEN1ALDH1A1HDAC3POLB | |
| SCHEMBL7027705 | 0.79 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1HDAC3CYP3A4 | |
| SCHEMBL23148484 | 0.77 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1HDAC3CYP3A4 | |
| SCHEMBL5162815 | 0.77 | HDAC3 (0.48) | KMT2AMEN1ALDH1A1HDAC3TSHR | |
| SCHEMBL5160718 | 0.76 | CYP3A4 (0.43) | ALDH1A1HDAC3CYP3A4CA2TSHR | |
| SCHEMBL2303601 | 0.76 | KMT2A (0.51) | KMT2AMEN1ALDH1A1HDAC3CYP3A4 | |
| SCHEMBL12368062 | 0.75 | ALDH1A1 (0.64) | KMT2AALDH1A1HDAC3CYP3A4CA2 | |
| SCHEMBL27938441 | 0.75 | ALDH1A1 (0.49) | KMT2AMEN1ALDH1A1HDAC3CYP3A4 | |
| SCHEMBL1427672 | 0.74 | CA2 (0.54) | ALDH1A1CYP3A4CA2TSHR | |
| SCHEMBL10633516 | 0.74 | KMT2A (0.45) | KMT2AMEN1ALDH1A1HDAC3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1340746-A1 | Process for the reduction of 3-heteroaryl-3-oxo-propanoic acid derivatives | BAYER AG (DE) | 2003-09-03 | — | — | EP | disclosed |