Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 7/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28547510 | 1.00 | KMT2A (0.53) | KMT2AMEN1NPC1ACELMNA | |
| SCHEMBL8622468 | 1.00 | KMT2A (0.53) | KMT2AMEN1NPC1ACELMNA | |
| SCHEMBL10735346 | 0.89 | KMT2A (0.48) | KMT2AMEN1NPC1ACELMNA | |
| SCHEMBL14182572 | 0.89 | KMT2A (0.48) | KMT2AMEN1NPC1LMNASLC6A2 | |
| SCHEMBL27612566 | 0.86 | KMT2A (0.40) | KMT2AMEN1NPC1ACELMNA | |
| SCHEMBL3370856 | 0.86 | KMT2A (0.60) | KMT2AMEN1NPC1ACELMNA | |
| SCHEMBL3370862 | 0.86 | KMT2A (0.60) | KMT2AMEN1NPC1ACELMNA | |
| SCHEMBL6025269 | 0.86 | KMT2A (0.60) | KMT2AMEN1NPC1ACELMNA | |
| SCHEMBL9864576 | 0.86 | POLB (0.48) | KMT2ASLC6A2SLC6A3TDP1POLB | |
| SCHEMBL10969556 | 0.85 | TACR1 (0.53) | ACELMNAL3MBTL1POLBTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789029-B1 | Improved procedure for the preparation of pure(S,S)-N-(1-Ethoxycarbonyl-3-phenylprophyl)-alanin). | DSM FINE CHEM AUSTRIA GMBH (AT) | 2003-09-10 | — | — | EP | claimed |
| US-5756812-A | Process for the preparation of pure (S,S)-N-(1-ethoxycarbonyl-3-phenylpropyl) alanine | DSM CHEMIE LINZ GMBH (AT) | 1998-05-26 | — | — | US | claimed |
| EP-0789029-A2 | Improved procedure for the preparation of pure(S,S)-N-(1-Ethoxycarbonyl-3-phenylprophyl)-alanin). | DSM Chemie Linz GmbH (AT) | 1997-08-13 | — | — | EP | claimed |
| CN-108147973-B | Preparation method of N- [1- (S) -ethoxycarbonyl-3-phenylpropyl ] -L-alanine | 凯莱英医药集团（天津）股份有限公司 | 2021-04-06 | — | — | CN | disclosed |
| US-7375245-B2 | N-(4-oxo-butanoic acid) -L-amino acid-ester derivatives and methods of preparation thereof | EVERLIGHT USA, INC. (US) | 2008-05-20 | — | — | US | disclosed |
| EP-0789029-B1 | Improved procedure for the preparation of pure(S,S)-N-(1-Ethoxycarbonyl-3-phenylprophyl)-alanin). | DSM FINE CHEM AUSTRIA GMBH (AT) | 2003-09-10 | — | — | EP | disclosed |
| US-5756812-A | Process for the preparation of pure (S,S)-N-(1-ethoxycarbonyl-3-phenylpropyl) alanine | DSM CHEMIE LINZ GMBH (AT) | 1998-05-26 | — | — | US | disclosed |
| EP-0789029-A2 | Improved procedure for the preparation of pure(S,S)-N-(1-Ethoxycarbonyl-3-phenylprophyl)-alanin). | DSM Chemie Linz GmbH (AT) | 1997-08-13 | — | — | EP | disclosed |