Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7100515 | 0.89 | MAPT (0.43) | ALDH1A1HPGDPOLBMAPTTDP1 | |
| SCHEMBL7101890 | 0.87 | MAPT (0.36) | ALDH1A1MAPTLMNACHRM1AKR1A1 | |
| SCHEMBL7102235 | 0.85 | TSHR (0.36) | ALDH1A1MAPTSMN1; SMN2TSHR | |
| SCHEMBL7099340 | 0.85 | CA1 (0.40) | ALDH1A1HPGDMAPTCHRM1AKR1A1 | |
| SCHEMBL7101044 | 0.84 | ALDH1A1 (0.41) | ALDH1A1HPGDMAPTLMNAHSD17B10 | |
| SCHEMBL7100406 | 0.84 | ALDH1A1 (0.42) | ALDH1A1HPGDMAPTLMNAL3MBTL1 | |
| SCHEMBL7096505 | 0.83 | LMNA (0.35) | MAPTLMNACHRM1AKR1A1CHRM3 | |
| SCHEMBL11531078 | 0.81 | ALDH1A1 (0.42) | ALDH1A1POLBMAPTLMNAHSD17B10 | |
| SCHEMBL6247104 | 0.79 | ALDH1A1 (0.40) | ALDH1A1HPGDMAPTLMNAHSD17B10 | |
| SCHEMBL5074743 | 0.79 | ALDH1A1 (0.40) | ALDH1A1HPGDMAPTLMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1038861-B1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-6593488-B1 | Reacting 2-fluorocarboxylate with carboxylate | UBE INDUSTRIES, LTD. (JP) | 2003-07-15 | — | — | US | disclosed |
| EP-1038861-A1 | 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME | UBE INDUSTRIES LIMITED (JP) | 2000-09-27 | — | — | EP | disclosed |