Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.71 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | RELA | Q04206 | 2/20 | 0.62 |
| ▸ | PDE4A | P27815 | 1/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.61 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.61 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.61 |
| ▸ | JUN | P05412 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22721804 | 1.00 | ABCG2 (0.71) | ABCG2PTPN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL29391850 | 1.00 | ABCG2 (0.71) | ABCG2PTPN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL7099971 | 0.90 | MAPT (0.74) | ABCG2PTPN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL7188211 | 0.90 | ABCG2 (0.79) | ABCG2PTPN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL7188219 | 0.90 | ABCG2 (0.79) | ABCG2PTPN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL7099538 | 0.86 | ABCG2 (0.86) | ABCG2PTPN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL7097238 | 0.86 | PTPN1 (0.74) | ABCG2PTPN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL20565018 | 0.86 | ABCG2 (0.86) | ABCG2PTPN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL29394843 | 0.86 | ABCG2 (0.86) | ABCG2PTPN1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL7096880 | 0.86 | NR1H4 (0.74) | PTPN1MAPTSMN1; SMN2KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003097577-A1 | CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME | SYNTH'E163 (SOCIETE ANONYME) (FR) | 2003-11-27 | — | — | WO | claimed |
| WO-2003097577-A1 | CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME | SYNTH'E163 (SOCIETE ANONYME) (FR) | 2003-11-27 | — | — | WO | disclosed |