SCHEMBL20565018

SCHEMBL20565018

COc1ccc(OC)c(/C=C/C(=O)c2ccc(N)cc2)c1

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 2/20 0.86
KDM4E B2RXH2 1/20 0.76
LMNA P02545 1/20 0.76
MAPT P10636 1/20 0.76
ATM Q13315 1/20 0.76
SMN1; SMN2 Q16637 1/20 0.76
L3MBTL1 Q9Y468 1/20 0.76
TNFRSF1A P19438 1/20 0.67
RELA Q04206 2/20 0.66
PDE4A P27815 1/20 0.65
PDE4B Q07343 1/20 0.65
PDE4C Q08493 1/20 0.65
PDE4D Q08499 1/20 0.65
JUN P05412 1/20 0.65
NFKB1 P19838 1/20 0.65
CTSL P07711 1/20 0.64
CTSB P07858 1/20 0.64
PTPN1 P18031 1/20 0.64
CA1 P00915 1/20 0.64
CA2 P00918 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7099538 1.00 ABCG2 (0.86) ABCG2KDM4ELMNAMAPTATM
SCHEMBL29394843 1.00 ABCG2 (0.86) ABCG2KDM4ELMNAMAPTATM
SCHEMBL7185006 0.92 ABCG2 (0.97) ABCG2KDM4ELMNAMAPTATM
SCHEMBL7185011 0.92 ABCG2 (0.97) ABCG2KDM4ELMNAMAPTATM
SCHEMBL7100049 0.89 TNFRSF1A (0.84) ABCG2KDM4ELMNAMAPTATM
SCHEMBL7192054 0.89 TNFRSF1A (0.84) ABCG2KDM4ELMNAMAPTATM
SCHEMBL6352780 0.88 ABCG2 (0.89) ABCG2KDM4ELMNAMAPTATM
SCHEMBL6352783 0.88 ABCG2 (0.89) ABCG2KDM4ELMNAMAPTATM
SCHEMBL30307319 0.88 ABCG2 (0.89) ABCG2KDM4ELMNAMAPTATM
SCHEMBL19182869 0.86 LMNA (1.00) ABCG2KDM4ELMNAMAPTATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250376441-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT UNIV YONSEI IACF (KR) 2025-12-11 US disclosed
US-12447137-B2 Composition for prevention, amelioration, or treatment of cancer EWHA University—Industry Collaboration Foundation (KR) 2025-10-21 US disclosed
US-20220226263-A1 Composition for Prevention, Amelioration, or Treatment of Cancer CHA UNIVERSITY INDUSTRY-ACADEMIC COOOPERATION FOUNDATION (KR) 2022-07-21 US disclosed
EP-3977988-A1 COMPOSITION FOR PREVENTION, AMELIORATION, OR TREATMENT OF CANCER Ewha University-Industry Collaboration Foundation (KR) 2022-04-06 EP disclosed
WO-2020242201-A1 COMPOSITION FOR PREVENTION, AMELIORATION, OR TREATMENT OF CANCER 이화여자대학교 산학협력단 2020-12-03 WO disclosed
WO-2020184998-A1 COMPOSITION FOR PREVENTING, ALLEVIATING OR TREATING METABOLIC DISEASES 연세대학교 산학협력단 2020-09-17 WO disclosed
US-20200190024-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT CHA UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2020-06-18 US disclosed
US-20200190024-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT CHA UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2020-06-18 US disclosed
EP-3626703-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT Industry-Academic Cooperation Foundation, Yonsei University (KR) 2020-03-25 EP disclosed
WO-2018212368-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT 연세대학교 산학협력단 2018-11-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200190024-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT PRKAA1, PRKAA2, PRKAG1 ABCG2 913/4885KDM4E 3574/4885LMNA 1969/4885
US-20220226263-A1 Composition for Prevention, Amelioration, or Treatment of Cancer FABP2, FABP1, TSG101 ABCG2 4190/4885KDM4E 4208/4885LMNA 1370/4885
US-20250376441-A1 NOVEL COMPOUND AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT PRKAA1, PRKAA2, PRKAG1 ABCG2 913/4885KDM4E 3574/4885LMNA 1969/4885
US-12447137-B2 Composition for prevention, amelioration, or treatment of cancer GSTO1, FABP1, GSTK1 ABCG2 3481/4885KDM4E 4179/4885LMNA 837/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.