Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328879 | 0.82 | CA1 (0.34) | CA1CA2 | |
| SCHEMBL17245272 | 0.79 | SMN1; SMN2 (0.39) | CA1CA2 | |
| SCHEMBL17245271 | 0.79 | SMN1; SMN2 (0.39) | CA1CA2 | |
| SCHEMBL11128828 | 0.79 | CA1 (0.31) | CA1CA2 | |
| SCHEMBL13484735 | 0.79 | SMN1; SMN2 (0.39) | CA1CA2 | |
| SCHEMBL18135532 | 0.77 | CA1 (0.30) | CA1CA2 | |
| SCHEMBL29896368 | 0.77 | CA1 (0.31) | CA1CA2 | |
| SCHEMBL26077665 | 0.76 | ALDH1A1 (0.39) | CA1CA2LMNAHSD17B10ALOX15 | |
| SCHEMBL12057007 | 0.76 | CA1 (0.44) | CA1CA2 | |
| SCHEMBL228308 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815084-B1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | EP | disclosed |