⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9540998 | 0.80 | — | — | |
| SCHEMBL21304164 | 0.79 | — | — | |
| SCHEMBL1392322 | 0.78 | CA1 (0.33) | — | |
| SCHEMBL27416714 | 0.77 | — | — | |
| SCHEMBL22090190 | 0.77 | LMNA (0.40) | — | |
| SCHEMBL6395180 | 0.77 | — | — | |
| SCHEMBL3396230 | 0.77 | — | — | |
| SCHEMBL6376109 | 0.77 | L3MBTL1 (0.33) | — | |
| SCHEMBL16908584 | 0.77 | CA2 (0.52) | — | |
| SCHEMBL25582929 | 0.77 | CA2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150101-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING N-[2-((2R)-2-{[4-[(4-CHLOROPHENYL)METHYL]-L-OXO-2(IH)-PHTHALAZ INYL]METHYL}-L- PYRROLIDINYL)ETHYL]-4-(METHYLOXY)BUTANAMIDE | GLAXO GROUP LIMITED (GB) | 2009-12-17 | — | — | WO | claimed |
| EP-1761519-B1 | INDOLE DERIVATIVES AS HISTAMINE RECEPTOR ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2008-05-07 | — | — | EP | claimed |
| US-6617483-B1 | Extractive distillation for separating a mixture of hydrocarbons with an alkylene glycol and a compatibility agent having polar parameters and hydrogen bonding parameters that result in improved separation | GAYLORD CHEMICAL CORPORATION | 2003-09-09 | — | — | US | claimed |
| WO-1999020617-A1 | ANTIINFLAMMATORY THIADIAZOLYL UREAS WHICH ACT AS LFA-1 AND MAC-1 INHIBITORS | ACTIVE BIOTECH AB (SE) | 1999-04-29 | — | — | WO | claimed |
| US-20230192673-A1 | Compounds | STEP PHARMA S.A.S. (FR) | 2023-06-22 | — | — | US | disclosed |
| CN-114561440-B | Preparation method of high-purity (R) - (+) -1- (4-methoxyphenylethyl amine monomer | 天津全和诚科技有限责任公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-114561440-A | Preparation method of high-purity (R) - (+) -1- (4-methoxyphenylethyl amine monomer | 天津全和诚科技有限责任公司 | 2022-05-31 | — | — | CN | disclosed |
| WO-2021018012-A1 | IRAK4 KINASE INHIBITOR AND PREPARATION METHOD THEREFOR | 珠海宇繁生物科技有限责任公司 | 2021-02-04 | — | — | WO | disclosed |
| US-20210024507-A1 | Compounds | STEP PHARMA S A S (FR) | 2021-01-28 | — | — | US | disclosed |
| CN-110062761-A | Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and their use as GLUN2B receptor modulators | 詹森药业有限公司 | 2019-07-26 | — | — | CN | disclosed |
| CN-108715594-A | Micro RNA inhibitors | 株式会社博纳克 | 2018-10-30 | — | — | CN | disclosed |
| US-RE47078-E1 | Polymorphic forms of N-[4-(trifluoromethyl)benzyl]-4-methoxybutyramide | LABORATORIO FARMACEUTICO C.T. S.R.L. (IT) | 2018-10-09 | — | — | US | disclosed |
| CN-1775759-A | Bicyclic androgen and progesterone receptor modulator compounds and methods | LIGAND PHARM INC (US) | 2006-05-24 | — | — | CN | disclosed |
| US-6967196-B1 | Sulfonamide compounds and uses thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-22 | — | — | US | disclosed |
| US-6617483-B1 | Extractive distillation for separating a mixture of hydrocarbons with an alkylene glycol and a compatibility agent having polar parameters and hydrogen bonding parameters that result in improved separation | GAYLORD CHEMICAL CORPORATION | 2003-09-09 | — | — | US | disclosed |
| CN-1382124-A | Bicyclic androgen and progesterone receptor modulating compounds and methods | LIGAND PHARM INC (US) | 2002-11-27 | — | — | CN | disclosed |
| EP-1212303-A2 | BICYCLIC ANDROGEN AND PROGESTERONE RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001016108-A2 | BICYCLIC ANDROGEN AND PROGESTERONE RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 2001-03-08 | — | — | WO | disclosed |
| CN-1064077-A | Bicyclic ethers with weeding activity | DU PONT (US) | 1992-09-02 | — | — | CN | disclosed |
| US-4386935-A | Process for producing discharge reserve prints on textile materials with amino-azo-benzene dyes | CASSELLA AKTIENGESELLSCHAFT (DE) | 1983-06-07 | — | — | US | disclosed |