Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | NPC1 | O15118 | 3/20 | 0.71 |
| ▸ | RAB9A | P51151 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.71 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.58 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7097768 | 0.91 | ABCG2 (0.68) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7198467 | 0.87 | MAPT (0.82) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7198465 | 0.87 | MAPT (0.82) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7186162 | 0.86 | TNFRSF1A (0.80) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7099543 | 0.86 | NR1H4 (0.70) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7097175 | 0.86 | TNFRSF1A (0.80) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7100718 | 0.86 | ABCG2 (0.66) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7100777 | 0.85 | ABCG2 (0.67) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7188111 | 0.83 | MAPT (1.00) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7188106 | 0.83 | MAPT (1.00) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003097577-A1 | CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME | SYNTH'E163 (SOCIETE ANONYME) (FR) | 2003-11-27 | — | — | WO | claimed |
| WO-2003097577-A1 | CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME | SYNTH'E163 (SOCIETE ANONYME) (FR) | 2003-11-27 | — | — | WO | disclosed |