Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.57 |
| ▸ | SNCA | P37840 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | DPP4 | P27487 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099543 | 0.87 | NR1H4 (0.70) | MAPTLMNAHPGDHTTATM | |
| SCHEMBL7097770 | 0.86 | MAPT (0.71) | ABCG2PTPN1MAPTLMNAHPGD | |
| SCHEMBL7097768 | 0.86 | ABCG2 (0.68) | ABCG2PTPN1MAPTLMNAHPGD | |
| SCHEMBL7099872 | 0.85 | ABCG2 (0.81) | ABCG2PTPN1SNCAMAPTLMNA | |
| SCHEMBL7096590 | 0.85 | NPC1 (0.66) | ABCG2MAPTLMNAHPGDHTT | |
| SCHEMBL7100564 | 0.84 | ABCG2 (0.67) | ABCG2PTPN1MAPTLMNAHPGD | |
| SCHEMBL7097596 | 0.84 | ABCG2 (0.66) | ABCG2MAPTLMNAHPGDHTT | |
| SCHEMBL29803110 | 0.83 | NR1H4 (0.76) | ABCG2PTPN1SNCADPP4NR1H4 | |
| SCHEMBL28556583 | 0.83 | PTPN1 (0.73) | ABCG2PTPN1SNCAMAPTLMNA | |
| SCHEMBL21643306 | 0.83 | NR1H4 (0.76) | ABCG2PTPN1SNCADPP4NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003097577-A1 | CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME | SYNTH'E163 (SOCIETE ANONYME) (FR) | 2003-11-27 | — | — | WO | claimed |
| WO-2003097577-A1 | CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME | SYNTH'E163 (SOCIETE ANONYME) (FR) | 2003-11-27 | — | — | WO | disclosed |