Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27639332 | 0.69 | PDE7A (0.46) | CES1 | |
| SCHEMBL6309542 | 0.65 | PDE7A (0.50) | — | |
| SCHEMBL14718279 | 0.65 | PDE3B (0.38) | CES1 | |
| SCHEMBL6280376 | 0.63 | GAA (0.37) | CES1 | |
| SCHEMBL11713736 | 0.63 | KDM4E (0.42) | — | |
| SCHEMBL8171311 | 0.61 | — | — | |
| SCHEMBL6342422 | 0.61 | BCAT2 (0.35) | — | |
| SCHEMBL21530513 | 0.61 | CA1 (0.42) | — | |
| SCHEMBL6679458 | 0.61 | TGM2 (0.43) | CES1 | |
| SCHEMBL14190067 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1301493-A2 | HETEROCYCLE CARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2003-04-16 | — | — | EP | disclosed |
| WO-2002004444-A2 | HETEROCYCLE CARBOXAMIDES AS ANTIVIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 2002-01-17 | — | — | WO | disclosed |