Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7105012 | 1.00 | TSHR (0.40) | TSHRALDH1A1CNR2FAAHTDP1 | |
| SCHEMBL2258455 | 0.91 | TSHR (0.35) | TSHRALDH1A1CNR2TDP1MEN1 | |
| SCHEMBL7097400 | 0.85 | CA1 (0.43) | TSHRALDH1A1CNR2FAAHTDP1 | |
| SCHEMBL7097527 | 0.85 | CA1 (0.43) | TSHRALDH1A1CNR2FAAHTDP1 | |
| SCHEMBL7105033 | 0.84 | TSHR (0.44) | TSHRALDH1A1CNR2FAAHTDP1 | |
| SCHEMBL7098991 | 0.84 | TSHR (0.44) | TSHRALDH1A1CNR2FAAHTDP1 | |
| SCHEMBL31299705 | 0.82 | TSHR (0.48) | TSHRALDH1A1CNR2FAAHTDP1 | |
| SCHEMBL31299677 | 0.82 | TSHR (0.48) | TSHRALDH1A1CNR2FAAHTDP1 | |
| SCHEMBL31299683 | 0.82 | TSHR (0.48) | TSHRALDH1A1CNR2FAAHTDP1 | |
| SCHEMBL31299720 | 0.82 | TSHR (0.48) | TSHRALDH1A1CNR2FAAHTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020443-B1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | AZWELL INC (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-6172228-B1 | Process for producing piperazinesulfonamide derivatives and salts thereof | AZWELL INC. (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-1020443-A1 | PROCESS FOR PRODUCING PIPERAZINESULFONAMIDE DERIVATIVES AND SALTS THEREOF | Azwell Inc. (JP) | 2000-07-19 | — | — | EP | disclosed |