Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25123985 | 0.77 | CA14 (0.40) | HDAC6HDAC1HDAC2ALDH1A1LMNA | |
| SCHEMBL24340294 | 0.76 | HDAC6 (0.37) | HDAC6HDAC1HDAC2ALDH1A1LMNA | |
| SCHEMBL25124155 | 0.74 | HDAC6 (0.33) | HDAC6 | |
| SCHEMBL4149715 | 0.73 | ALDH1A1 (0.42) | HDAC6HDAC1HDAC2ALDH1A1LMNA | |
| SCHEMBL30304345 | 0.73 | ALDH1A1 (0.42) | HDAC6HDAC1HDAC2ALDH1A1LMNA | |
| SCHEMBL30304722 | 0.73 | ALDH1A1 (0.42) | HDAC6HDAC1HDAC2ALDH1A1LMNA | |
| SCHEMBL31716325 | 0.72 | ALDH1A1 (0.35) | HDAC6HDAC1HDAC2ALDH1A1LMNA | |
| SCHEMBL2526136 | 0.72 | HDAC6 (0.39) | HDAC6HDAC1HDAC2ALDH1A1LMNA | |
| SCHEMBL3423361 | 0.71 | CA14 (0.38) | HDAC6HDAC1HDAC2 | |
| SCHEMBL637189 | 0.70 | ALDH1A1 (0.53) | HDAC6HDAC1HDAC2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815084-B1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | PROCTER & GAMBLE (US) | 2003-08-27 | — | — | EP | disclosed |
| US-5672598-A | MATRIX METALLOPROTEASE INHIBITORS | THE PROCTER & GAMBLE COMPANY (US) | 1997-09-30 | — | — | US | disclosed |