SCHEMBL7098544

SCHEMBL7098544

Nc1cccc(-c2cc(N)c(N)c(N)c2N)c1N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CD44 P16070 1/20 0.39
CYP3A4 P08684 5/20 0.35
HSD17B10 Q99714 3/20 0.35
TSHR P16473 3/20 0.35
HPGD P15428 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
CASP1 P29466 2/20 0.33
ALOX15 P16050 1/20 0.33
CASP7 P55210 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PIK3CA P42336 1/20 0.33
PTPRC P08575 1/20 0.33
ADORA2A P29274 1/20 0.33
MAOA P21397 1/20 0.31
MAOB P27338 1/20 0.31
PDK2 Q15119 1/20 0.31
RECQL P46063 1/20 0.31
KEAP1 Q14145 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7545678 0.87 ALDH1A1 (0.54) ALDH1A1L3MBTL1CD44CYP3A4HSD17B10
SCHEMBL6228512 0.84 ALDH1A1 (0.62) ALDH1A1L3MBTL1CYP3A4HSD17B10TSHR
SCHEMBL6228503 0.83 ALDH1A1 (0.46) ALDH1A1L3MBTL1CD44CYP3A4HSD17B10
SCHEMBL560128 0.83 ALDH1A1 (0.56) ALDH1A1L3MBTL1CD44CYP3A4HSD17B10
SCHEMBL31554259 0.82 ALDH1A1 (0.35) ALDH1A1L3MBTL1CD44CYP3A4HSD17B10
SCHEMBL28345869 0.82 ALDH1A1 (0.35) ALDH1A1L3MBTL1CD44CYP3A4HSD17B10
Hydrochloric Acid SCHEMBL4521251 0.80 ALDH1A1 (0.53) ALDH1A1L3MBTL1CD44CYP3A4HSD17B10
Methane SCHEMBL22720568 0.80 ALDH1A1 (0.53) ALDH1A1L3MBTL1CD44CYP3A4HSD17B10
SCHEMBL28448451 0.78 ALDH1A1 (0.58) ALDH1A1L3MBTL1CD44CYP3A4HSD17B10
SCHEMBL2224609 0.75 ALDH1A1 (0.72) ALDH1A1L3MBTL1CD44CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2003119172-A NEW COMPOUND HAVING SKELETON OF TETRAKISAMINOPHENYL(DI) PHENYLENE DIAMINE AND METHOD OF USING THE SAME NIPPON KAYAKU CO LTD 2003-04-23 JP disclosed
JP-2002212066-A NEW PHOTOCHEMOTHERAPEUTIC AGENT NIPPON KAYAKU CO LTD 2002-07-31 JP disclosed
JP-2002173474-A NEW COMPOUND HAVING TETRAKISAMINOPHENYL (DI) PHENYLENEDIAMINE SKELETON NIPPON KAYAKU CO LTD 2002-06-21 JP disclosed