Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | CPA1 | P15085 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | GPR132 | Q9UNW8 | 6/20 | 0.52 |
| ▸ | GPR34 | Q9UPC5 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | CMKLR2 | P46091 | 1/20 | 0.44 |
| ▸ | CMKLR1 | Q99788 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | YAP1 | P46937 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7098661 | 1.00 | MME (0.53) | MMEACECPA1ACE2GPR132 | |
| SCHEMBL7101959 | 0.91 | PPARG (0.54) | MMEACECPA1ACE2GPR132 | |
| SCHEMBL7101955 | 0.91 | PPARG (0.54) | MMEACECPA1ACE2GPR132 | |
| SCHEMBL7103977 | 0.85 | MEN1 (0.48) | MMEACECPA1ACE2GPR34 | |
| SCHEMBL7102219 | 0.84 | PPARG (0.54) | NPSR1MEN1KMT2APPARGYAP1 | |
| SCHEMBL7102218 | 0.84 | PPARG (0.54) | NPSR1MEN1KMT2APPARGYAP1 | |
| SCHEMBL7097645 | 0.84 | MME (0.49) | MMEACECPA1ACE2NPSR1 | |
| SCHEMBL7100731 | 0.81 | MEN1 (0.48) | GPR34NPSR1MEN1KMT2AADAM17 | |
| SCHEMBL7100733 | 0.81 | MEN1 (0.48) | GPR34NPSR1MEN1KMT2AADAM17 | |
| SCHEMBL7098305 | 0.81 | ITGA4 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991619-B1 | INHIBITORS OF ALPHA 4-BETA 1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2003-09-10 | — | — | EP | claimed |