Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.46 |
| ▸ | GPR34 | Q9UPC5 | 4/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | YAP1 | P46937 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7101955 | 0.92 | PPARG (0.54) | MEN1KMT2ANPSR1PPARGGPR34 | |
| SCHEMBL7101959 | 0.92 | PPARG (0.54) | MEN1KMT2ANPSR1PPARGGPR34 | |
| SCHEMBL7097645 | 0.91 | MME (0.49) | MEN1KMT2ANPSR1MMEACE | |
| SCHEMBL7100733 | 0.88 | MEN1 (0.48) | MEN1KMT2ANPSR1GPR34MAOB | |
| SCHEMBL7100731 | 0.88 | MEN1 (0.48) | MEN1KMT2ANPSR1GPR34MAOB | |
| SCHEMBL7102218 | 0.85 | PPARG (0.54) | MEN1KMT2ANPSR1PPARGYAP1 | |
| SCHEMBL7102219 | 0.85 | PPARG (0.54) | MEN1KMT2ANPSR1PPARGYAP1 | |
| SCHEMBL7098661 | 0.85 | MME (0.53) | MEN1KMT2ANPSR1PTPN1PPARG | |
| SCHEMBL7098660 | 0.85 | MME (0.53) | MEN1KMT2ANPSR1PTPN1PPARG | |
| SCHEMBL7098304 | 0.84 | ITGA4 (0.61) | ITGA4ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991619-B1 | INHIBITORS OF ALPHA 4-BETA 1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2003-09-10 | — | — | EP | claimed |