Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 16/20 | 0.77 |
| ▸ | MTNR1B | P49286 | 14/20 | 0.77 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006961 | 1.00 | MTNR1A (0.77) | MTNR1AMTNR1BABL1NQO2KDM4E | |
| SCHEMBL7094759 | 0.87 | MTNR1A (1.00) | MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL7012333 | 0.87 | MTNR1A (1.00) | MTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL7011682 | 0.86 | MTNR1A (0.77) | MTNR1AMTNR1B | |
| SCHEMBL7231439 | 0.86 | MTNR1A (0.77) | MTNR1AMTNR1B | |
| SCHEMBL7235613 | 0.83 | MTNR1A (0.76) | MTNR1AMTNR1B | |
| SCHEMBL7007743 | 0.83 | MTNR1A (0.76) | MTNR1AMTNR1B | |
| SCHEMBL7229523 | 0.76 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7231435 | 0.76 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL7236200 | 0.73 | MTNR1A (0.61) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583319-B1 | Treating or preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-06-24 | — | — | US | disclosed |
| EP-0994102-B1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-19 | — | — | EP | disclosed |
| EP-0994102-A1 | Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-04-19 | — | — | EP | disclosed |