SCHEMBL7011682

SCHEMBL7011682

CCC(=O)NC1CC1c1cccc2ccc(OC)cc12

nearest known ligand 0.77

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 17/20 0.77
MTNR1B P49286 9/20 0.77
HTR2C P28335 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7231439 1.00 MTNR1A (0.77) MTNR1AMTNR1BHTR2C
SCHEMBL7235613 0.92 MTNR1A (0.76) MTNR1AMTNR1B
SCHEMBL7007743 0.92 MTNR1A (0.76) MTNR1AMTNR1B
SCHEMBL7012333 0.87 MTNR1A (1.00) MTNR1AMTNR1BHTR2C
SCHEMBL7094759 0.87 MTNR1A (1.00) MTNR1AMTNR1BHTR2C
SCHEMBL7006961 0.86 MTNR1A (0.77) MTNR1AMTNR1B
SCHEMBL7098772 0.86 MTNR1A (0.77) MTNR1AMTNR1B
SCHEMBL7230327 0.82 MTNR1A (0.77) MTNR1AMTNR1B
SCHEMBL7010965 0.82 MTNR1A (0.77) MTNR1AMTNR1B
SCHEMBL7238143 0.80 MTNR1A (0.51) MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6583319-B1 Treating or preventing melatoninergic disorders LES LABORATOIRES SERVIER (FR) 2003-06-24 US claimed
EP-0994102-B1 Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2003-03-19 EP claimed
EP-0994102-A1 Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 2000-04-19 EP claimed
US-6583319-B1 Treating or preventing melatoninergic disorders LES LABORATOIRES SERVIER (FR) 2003-06-24 US disclosed
EP-0994102-B1 Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them SERVIER LAB (FR) 2003-03-19 EP disclosed
EP-0994102-A1 Cyclic derivatives with a cycloalkylenic chain, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 2000-04-19 EP disclosed