Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099446 | 1.00 | MAPT (0.47) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL27454538 | 1.00 | MAPT (0.47) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL7664314 | 0.96 | ALDH1A1 (0.48) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL7664316 | 0.96 | ALDH1A1 (0.48) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL7104365 | 0.95 | MAPT (0.47) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL27466190 | 0.95 | MAPT (0.47) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL7104362 | 0.95 | MAPT (0.47) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL7107475 | 0.95 | MAPT (0.47) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL7107477 | 0.95 | MAPT (0.47) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL7103310 | 0.93 | MEN1 (0.47) | MAPTALDH1A1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000939-B1 | Producing z-isomer of hydrogen bromide salt of 2-aminothiazole derivative | SUMITOMO CHEMICAL CO (JP) | 2003-09-17 | — | — | EP | disclosed |
| US-6403572-B1 | REACTING ACID SALT OF A 2-AMINOTHIAZOLE COMPOUND WITH INORGANIC ACID | SUMITOMO CHEMICAL CO., LTD. (JP) | 2002-06-11 | — | — | US | disclosed |
| US-20020058818-A1 | Producing Z-isomer of hydrogen bromide salt of 2-aminothiazole derivative | SUMITOMO CHEMICAL CO., LTD. | 2002-05-16 | — | — | US | disclosed |
| US-6340763-B1 | SALT FORMATION AND CRYSTALLIZATION, REACTION OF HALOGENATED COMPOUND AND THIOUREA COMPOUND | SUMITOMO CHEMICAL CO., LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-1000939-A1 | Producing z-isomer of hydrogen bromide salt of 2-aminothiazole derivative | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-05-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058818-A1 | Producing Z-isomer of hydrogen bromide salt of 2-aminothiazole derivative | ZYX, H1-0, HAO2 | MAPT 1584/4885ALDH1A1 2333/4885RAB9A 540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.