Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | DBH | P09172 | 1/20 | 0.39 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5982678 | 0.79 | CYP11B1 (0.56) | SMN1; SMN2LMNAHTTNPC1KMT2A | |
| SCHEMBL5982570 | 0.77 | CYP11B1 (0.51) | LMNANPC1RAB9APOLBALDH1A1 | |
| SCHEMBL5306461 | 0.77 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNAHTTNPC1RAB9A | |
| SCHEMBL5983231 | 0.73 | KDM4E (0.46) | SMN1; SMN2SIGMAR1IDO1ALDH1A1MAPT | |
| SCHEMBL5982812 | 0.73 | SIGMAR1 (0.51) | SMN1; SMN2LMNAPOLBKMT2ASIGMAR1 | |
| SCHEMBL27944073 | 0.71 | CYP11B1 (0.69) | POLBMAPT | |
| SCHEMBL13692163 | 0.71 | SMN1; SMN2 (0.68) | SMN1; SMN2LMNAHTTNPC1RAB9A | |
| SCHEMBL5982487 | 0.69 | LPO (0.52) | LMNAKMT2ASIGMAR1IDO1MEN1 | |
| SCHEMBL15652733 | 0.68 | KMT2A (0.54) | SMN1; SMN2LMNAHTTNPC1RAB9A | |
| SCHEMBL2089216 | 0.67 | NOTUM (0.43) | SMN1; SMN2LMNATSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991619-B1 | INHIBITORS OF ALPHA 4-BETA 1 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2003-09-10 | — | — | EP | disclosed |