Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 5/20 | 0.36 |
| ▸ | THRA | P10827 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28965932 | 0.87 | TSHR (0.40) | ALDH1A1THRBTHRATSHRCYP3A4 | |
| SCHEMBL14173186 | 0.84 | ALDH1A1 (0.47) | ALDH1A1THRBTHRATSHRALOX15 | |
| SCHEMBL14173129 | 0.84 | AR (0.33) | ALDH1A1TSHRCYP3A4HIF1ATDP1 | |
| SCHEMBL14340308 | 0.84 | ALDH1A1 (0.49) | ALDH1A1THRBTHRATSHRALOX15 | |
| SCHEMBL10883794 | 0.83 | ALDH1A1 (0.46) | ALDH1A1THRBTHRATSHRALOX15 | |
| SCHEMBL3938199 | 0.81 | ALDH1A1 (0.49) | ALDH1A1THRBTHRATSHRALOX15 | |
| SCHEMBL6993149 | 0.80 | ALDH1A1 (0.38) | ALDH1A1TSHRALOX15ALOX12CYP3A4 | |
| SCHEMBL14565106 | 0.78 | ALDH1A1 (0.41) | ALDH1A1THRBTHRA | |
| SCHEMBL372646 | 0.77 | THRB (0.46) | ALDH1A1THRBTHRATSHRALOX15 | |
| SCHEMBL14173111 | 0.77 | AR (0.46) | ALDH1A1HIF1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0441383-B1 | Use of a copolymer for the making of contact lenses | MITSUBISHI RAYON CO (JP) | 1996-05-08 | — | — | EP | claimed |
| EP-0730168-B1 | Film-forming coating solution and synthetic resin lens | SEIKO EPSON CORP (JP) | 2003-09-03 | — | — | EP | disclosed |
| EP-0273710-A2 | Resin having high refractive index, process for producing said resin and optical materials composed of said resin | Nippon Shokubai Kagaku Kogyo Co., Ltd (JP) | 1988-07-06 | — | — | EP | disclosed |