Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1625262 | 0.79 | PPARG (0.42) | TLR8NR1H2NR1H3PPARGPOLB | |
| SCHEMBL1624340 | 0.76 | TAAR1 (0.40) | TLR8NR1H2NR1H3GAAPPARG | |
| SCHEMBL1624698 | 0.76 | PPARG (0.40) | TLR8NR1H2NR1H3PPARGMEN1 | |
| SCHEMBL9270163 | 0.73 | LMNA (0.53) | TLR8ALDH1A1PPARGMAPK1 | |
| SCHEMBL10815729 | 0.72 | PPARG (0.47) | TLR8PPARGPOLBMEN1KMT2A | |
| SCHEMBL1625879 | 0.72 | FAAH (0.42) | NR1H2NR1H3PPARGMEN1KMT2A | |
| SCHEMBL27582837 | 0.72 | NR1H2 (0.39) | ALDH1A1NR1H2NR1H3TSHRPPARG | |
| SCHEMBL9847092 | 0.70 | TLR8 (0.48) | TLR8TSHRGAAPPARGNPC1 | |
| SCHEMBL7104173 | 0.69 | MAPT (0.37) | ALDH1A1NR1H2NR1H3TSHRGAA | |
| SCHEMBL1271724 | 0.68 | NR1H2 (0.54) | NR1H2NR1H3PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326864-A2 | ARYL OR HETEROARYL FUSED IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002032900-A2 | ARYL OR HETEROARYL FUSED IMIDAZOLE COMPOUNDS AS ANTI-INFLAMMATORY AND ANALGESIC AGENTS | PFIZER PHARMACEUTICALS INC. (JP) | 2002-04-25 | — | — | WO | disclosed |