SCHEMBL7100416

SCHEMBL7100416

CCc1ccc(-c2ccc(-n3c4ccccc4c4ccccc43)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.53
ATM Q13315 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
POLB P06746 1/20 0.45
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
HDAC4 P56524 1/20 0.43
PARP1 P09874 1/20 0.41
AKR1C4 P17516 1/20 0.41
AKR1C3 P42330 1/20 0.41
AKR1C2 P52895 1/20 0.41
AKR1C1 Q04828 1/20 0.41
MAPK8 P45983 1/20 0.41
PTPN1 P18031 2/20 0.40
TP53 P04637 1/20 0.40
APOBEC3G Q9HC16 2/20 0.39
RXFP1 Q9HBX9 1/20 0.39
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
ADORA3 P0DMS8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10067476 0.94 KDM4E (0.59) KDM4EATML3MBTL1POLBNPC1
SCHEMBL10029892 0.92 KDM4E (0.46) KDM4EATML3MBTL1POLBNPC1
SCHEMBL22809252 0.92 KDM4E (0.48) KDM4EATML3MBTL1POLBNPC1
SCHEMBL7601627 0.92 KDM4E (0.48) KDM4EATML3MBTL1POLBNPC1
SCHEMBL16268823 0.90 KDM4E (0.47) KDM4EATML3MBTL1POLBHDAC4
SCHEMBL15138398 0.89 KDM4E (0.47) KDM4EATML3MBTL1POLBNPC1
SCHEMBL25624779 0.88 KDM4E (0.52) KDM4EATML3MBTL1POLBNPC1
SCHEMBL18234581 0.88 KDM4E (0.49) KDM4EATML3MBTL1POLBHDAC4
SCHEMBL13542510 0.88 KDM4E (0.49) KDM4EATML3MBTL1POLBHDAC4
SCHEMBL21077110 0.86 KDM4E (0.50) KDM4EATML3MBTL1POLBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8535863-B2 Electrophotographic photoreceptor, and image forming apparatus and process cartridge using same RICOH COMPANY, LTD. (JP) 2013-09-17 US disclosed
US-8535863-B2 Electrophotographic photoreceptor, and image forming apparatus and process cartridge using same RICOH COMPANY, LTD. (JP) 2013-09-17 US disclosed
US-20120052424-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME RICOH COMPANY, LTD. (JP) 2012-03-01 US disclosed
US-20120052424-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE USING SAME RICOH COMPANY, LTD. (JP) 2012-03-01 US disclosed
US-7651790-B2 bipolar phosphorescent host containing 4,4'-biscarbazolylbiphenyl hole transport unit attached to electron transport unit selected from fluorene or spirofluorene and an aluminum hydroquinoline unit; phospherescent dopant e.g. tris(3-biphenylpyridine)Iridium; high efficiency and a long lifetime SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-01-26 US disclosed
US-20080145705-A1 Material for Organic Electroluminescent Element and Organic Electroluminescent Element Employing the Same TOYO INK MANUFACTURING CO., LTD. (JP) 2008-06-19 US disclosed
US-6528657-B2 For use in electroluminescence light emission element and can emit lights of various colors when an energy such as electric energy or electromagnetic energy is applied thereto TAIHO INDUSTRIES CO., LTD. (JP) 2003-03-04 US disclosed
US-20030023099-A1 Novel fluorescent carbazole derivative HIROSE ENGINEERING CO., LTD. (JP) 2003-01-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030023099-A1 Novel fluorescent carbazole derivative CBR3, AANAT, SIRT3 KDM4E 3224/4885ATM 3534/4885L3MBTL1 1222/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.