SCHEMBL10029892

SCHEMBL10029892

CCc1ccc(N(c2ccc(CC)cc2)c2ccc(-c3ccc(-n4c5ccccc5c5ccccc54)cc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
POLB P06746 2/20 0.41
HDAC4 P56524 1/20 0.39
RXFP1 Q9HBX9 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
AKR1C4 P17516 1/20 0.38
AKR1C3 P42330 1/20 0.38
AKR1C2 P52895 1/20 0.38
AKR1C1 Q04828 1/20 0.38
PARP1 P09874 1/20 0.37
PTPN1 P18031 1/20 0.36
MAPK8 P45983 1/20 0.36
PTAFR P25105 1/20 0.36
RXRA P19793 1/20 0.35
RXRB P28702 1/20 0.35
ADORA3 P0DMS8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15138398 0.97 KDM4E (0.47) KDM4EATML3MBTL1POLBHDAC4
SCHEMBL7100416 0.92 KDM4E (0.53) KDM4EATML3MBTL1POLBHDAC4
SCHEMBL16590735 0.91 TSPO (0.46) KDM4EATML3MBTL1POLBHDAC4
SCHEMBL17973785 0.90 KDM4E (0.41) KDM4EATML3MBTL1POLBHDAC4
SCHEMBL17987016 0.90 KDM4E (0.41) KDM4EATML3MBTL1POLBHDAC4
SCHEMBL16590734 0.90 TSPO (0.46) KDM4EATML3MBTL1POLBHDAC4
SCHEMBL12593224 0.89 L3MBTL1 (0.57) KDM4EATML3MBTL1POLBHDAC4
SCHEMBL1760465 0.89 L3MBTL1 (0.57) KDM4EATML3MBTL1POLBHDAC4
SCHEMBL10114571 0.89 L3MBTL1 (0.57) KDM4EATML3MBTL1POLBHDAC4
SCHEMBL12414472 0.89 L3MBTL1 (0.57) KDM4EATML3MBTL1POLBHDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11877464-B2 Organic light emitting element LG CHEM, LTD. (KR) 2024-01-16 US disclosed
US-11877464-B2 Organic light emitting element LG CHEM, LTD. (KR) 2024-01-16 US disclosed
US-11678571-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2023-06-13 US disclosed
US-11678571-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2023-06-13 US disclosed
US-20210376247-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2021-12-02 US disclosed
US-11152574-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2021-10-19 US disclosed
US-11094888-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle IDEMITSU KOSAN CO., LTD. (JP) 2021-08-17 US disclosed
US-20210135124-A1 ORGANIC LIGHT-EMITTING DEVICE AND METHOD OF MANUFACTURING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2021-05-06 US disclosed
US-20210083194-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2021-03-18 US disclosed
US-20200144552-A1 ORGANIC LIGHT EMITTING ELEMENT LG CHEM, LTD. (KR) 2020-05-07 US disclosed
US-20100301312-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. 2010-12-02 US disclosed
US-20100301312-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. 2010-12-02 US disclosed
EP-2224510-A1 ORGANIC ELECTROLUMINESCENT DEVICE Idemitsu Kosan Co., Ltd. (JP) 2010-09-01 EP disclosed
WO-2009081857-A1 ORGANIC ELECTROLUMINESCENT DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2009-07-02 WO disclosed
US-20090039769-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS SONY CORPORATION (JP) 2009-02-12 US disclosed
US-20090039769-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS SONY CORPORATION (JP) 2009-02-12 US disclosed
US-20080164809-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS SONY CORPORATION (JP) 2008-07-10 US disclosed
US-20080164809-A1 ORGANIC ELECTROLUMINESCENT DEVICE AND DISPLAY APPARATUS SONY CORPORATION (JP) 2008-07-10 US disclosed
US-20080014464-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2008-01-17 US disclosed
US-20080014464-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE IDEMITSU KOSAN CO., LTD. (JP) 2008-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11152574-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle RPL21, RPS21, AOC2 KDM4E 1889/4885ATM 3641/4885L3MBTL1 1564/4885
US-11678571-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle RPS17, RPS19, CDK17 KDM4E 502/4885ATM 1740/4885L3MBTL1 204/4885
US-11877464-B2 Organic light emitting element CACNA2D4, CYBA, L1CAM KDM4E 3566/4885ATM 2446/4885L3MBTL1 686/4885
US-20210083194-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE RPL21, RPS21, AOC2 KDM4E 1889/4885ATM 3641/4885L3MBTL1 1564/4885
US-11094888-B2 Organic electroluminescent device using aryl amine derivative containing heterocycle SLC18A1, SLC18A2, AOC2 KDM4E 2498/4885ATM 3497/4885L3MBTL1 2530/4885
US-20200144552-A1 ORGANIC LIGHT EMITTING ELEMENT CACNA2D4, CYBA, L1CAM KDM4E 3566/4885ATM 2446/4885L3MBTL1 686/4885
US-20210376247-A1 ORGANIC ELECTROLUMINESCENT DEVICE USING ARYL AMINE DERIVATIVE CONTAINING HETEROCYCLE RPS17, RPS19, CDK17 KDM4E 502/4885ATM 1740/4885L3MBTL1 204/4885
US-20100301312-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AOC2, SCO2, NUDC KDM4E 1692/4885ATM 2682/4885L3MBTL1 4190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.