Propionic Acid

Propionic Acid

SCHEMBL7100683

CCC(=O)O.NC1=CC(=O)C=CC1=O

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.40
ACHE P22303 1/20 0.35
BACE1 P56817 1/20 0.35
ERBB2 P04626 1/20 0.33
MAOA P21397 3/20 0.32
MAOB P27338 3/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
ALOX12 P18054 1/20 0.32
RECQL P46063 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
SETD7 Q8WTS6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL27286464 0.83 ERBB2 (0.41) ACHEBACE1ERBB2MAOAMAOB
Stearic Acid SCHEMBL27490217 0.81 GPR84 (0.53) ACHEBACE1MEN1ALDH1A1MAPT
SCHEMBL251013 0.80
Hydrochloric Acid SCHEMBL27713839 0.78 TDP1 (0.43) ACHEBACE1ERBB2MAOAMAOB
Hydrochloric Acid SCHEMBL27768191 0.78 TDP1 (0.43) ACHEBACE1ERBB2MAOAMAOB
Bromide SCHEMBL28772955 0.78 TDP1 (0.43) ACHEBACE1ERBB2MAOAMAOB
Benzoquinone SCHEMBL3738782 0.78 FFAR3 (0.59) FFAR3ACHEMAOAMAOBALDH1A1
Hydrochloric Acid SCHEMBL1694296 0.78 TDP1 (0.43) ACHEBACE1ERBB2MAOAMAOB
Butylamine SCHEMBL27886537 0.74 ACHE (0.46) ACHEBACE1ERBB2MEN1ALDH1A1
Propionic Acid SCHEMBL27638989 0.66 FFAR3 (0.56) FFAR3ACHEMAOAMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0988057-B1 BIOREDUCTIVE CONJUGATES FOR DRUG TARGETING UNIV MANCHESTER (GB) 2003-08-27 EP disclosed