SCHEMBL7097596

SCHEMBL7097596

CNc1cccc(C(=O)C=Cc2ccc(OC)c(OC)c2OC)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.66
CYP1A1 P04798 2/20 0.61
CYP1A2 P05177 2/20 0.61
CYP2D6 P10635 2/20 0.61
CYP1B1 Q16678 2/20 0.61
CYP3A4 P08684 1/20 0.61
NPC1 O15118 3/20 0.56
RAB9A P51151 3/20 0.56
SMN1; SMN2 Q16637 2/20 0.56
MAPT P10636 2/20 0.56
MAOB P27338 2/20 0.56
LMNA P02545 3/20 0.55
TP53 P04637 1/20 0.55
RELA Q04206 2/20 0.55
ALDH1A1 P00352 1/20 0.55
NTSR1 P30989 1/20 0.55
TDP1 Q9NUW8 1/20 0.55
ABCB1 P08183 1/20 0.53
HPGD P15428 1/20 0.53
HTT P42858 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7096590 0.92 NPC1 (0.66) ABCG2CYP1A1CYP1A2CYP2D6NPC1
SCHEMBL7102316 0.85 ABCG2 (0.82) ABCG2CYP1A1CYP1A2CYP2D6CYP1B1
SCHEMBL7100718 0.84 ABCG2 (0.66) ABCG2NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL21643397 0.84 ABCG2 (0.71) ABCG2CYP1A1CYP1A2CYP2D6CYP1B1
SCHEMBL29802986 0.84 ABCG2 (0.71) ABCG2CYP1A1CYP1A2CYP2D6CYP1B1
SCHEMBL7099543 0.84 NR1H4 (0.70) CYP1A1CYP1A2CYP2D6CYP1B1CYP3A4
SCHEMBL7097768 0.83 ABCG2 (0.68) ABCG2NPC1RAB9ASMN1; SMN2MAPT
SCHEMBL7097770 0.83 MAPT (0.71) ABCG2CYP1A1CYP1A2CYP2D6CYP1B1
SCHEMBL7097693 0.83 ABCG2 (0.69) ABCG2CYP1A1CYP1A2CYP2D6CYP1B1
SCHEMBL1764954 0.82 ABCG2 (0.86) ABCG2CYP1A1CYP1A2CYP2D6CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003097577-A1 CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME SYNTH'E163 (SOCIETE ANONYME) (FR) 2003-11-27 WO claimed
WO-2003097577-A1 CHEMICAL COMPOUND CONSISTING OF A NITROGENOUS CHALCONE DERIVATIVE, METHOD OF PRODUCING ONE SUCH CHEMICAL COMPOUND AND FILTERING AND/OR COSMETIC COMPOSITION CONTAINING SAME SYNTH'E163 (SOCIETE ANONYME) (FR) 2003-11-27 WO disclosed